Brain
in sentence
4290 examples of Brain in a sentence
All of these questions that philosophers have been studying for millennia, we scientists can begin to explore by doing
brain
imaging, and by studying patients and asking the right questions.
But it has this insanely earwormy tune, which I'm not going to play to you, because it will sear itself into your
brain
in the same way that it seared itself into mine, and I'm not going to do that to you.
We do know from fMRI studies that these hallucinations activate the same
brain
areas as sight, areas that are not activated by imagination.
Many other hallucinations, including smells, sights, and sounds, also involve the same
brain
areas as real sensory experiences.
But even in people with completely unimpaired senses, the
brain
constructs the world we perceive from incomplete information.
When the visual cortex is deprived of input from the eyes, even temporarily, the
brain
still tries to create a coherent picture, but the limits of its abilities become a lot more obvious.
Because Charles Bonnet Syndrome only occurs in people who had normal vision and then lost their sight, not those who were born blind, scientists think the
brain
uses remembered images to compensate for the lack of new visual input.
That’s likely because they activate receptors in a broad range of
brain
areas, including the cortical regions for all the senses.
LSD and psilocybin both function like serotonin in the brain, binding directly to one type of serotonin receptor in particular.
While serotonin’s role in the
brain
is complex and poorly understood, it likely plays an important part in integrating information from the eyes, nose, ears, and other sensory organs.
Patients with schizophrenia often have elevated levels of serotonin in the
brain.
They completely interrupt the communication between the
brain
and the spinal cord, thus leading to complete and permanent paralysis of the leg.
It turned out that more than 100 years of research on spinal cord physiology, starting with the Nobel Prize Sherrington, had shown that the spinal cord, below most injuries, contained all the necessary and sufficient neural networks to coordinate locomotion, but because input from the
brain
is interrupted, they are in a nonfunctional state, like kind of dormant.
It turned out that there are known neural pathways coming from the
brain
that play this very function during locomotion.
My idea: Replace this missing input to provide the spinal cord with the kind of intervention that the
brain
would deliver naturally in order to walk.
As soon as the treadmill belt starts moving, the animal shows coordinated movement of the leg, but without the
brain.
Here what I call "the spinal
brain"
cognitively processes sensory information arising from the moving leg and makes decisions as to how to activate the muscle in order to stand, to walk, to run, and even here, while sprinting, instantly stand if the treadmill stops moving.
I was completely fascinated by this locomotion without the brain, but at the same time so frustrated.
And it then became obvious from me that we had to move away from the classical rehabilitation paradigm, stepping on a treadmill, and develop conditions that would encourage the
brain
to begin voluntary control over the leg.
This novel training paradigm encouraged the
brain
to create new connections, some relay circuits that relay information from the
brain
past the injury and restore cortical control over the locomotor networks below the injury.
And here, you can see one such example, where we label the fibers coming from the
brain
in red.
This blue neuron is connected with the locomotor center, and what this constellation of synaptic contacts means is that the
brain
is reconnected with the locomotor center with only one relay neuron.
It occurred throughout the central nervous system, including in the
brain
stem, where we observed up to 300-percent increase in the density of fibers coming from the
brain.
My hope here is to be able to create the personalized condition to boost the plasticity of the
brain
and the spinal cord.
And this is a radically new concept that may apply to other neurological disorders, what I termed "personalized neuroprosthetics," where by sensing and stimulating neural interfaces, I implanted throughout the nervous system, in the brain, in the spinal cord, even in peripheral nerves, based on patient-specific impairments.
On St. Patrick's Day of 2008, I reported to the hospital for surgery to remove a
brain
tumor.
In particular, I thought about my dad, who had passed away from complications from
brain
surgery.
What is so special about the human
brain?
What does a human
brain
have or do that no other
brain
does?
Though it was based on very little evidence, many scientists thought that all mammalian brains, including the human brain, were made in the same way, with a number of neurons that was always proportional to the size of the
brain.
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