Brain
in sentence
4290 examples of Brain in a sentence
First, you find and label a memory in the brain, and then you activate it with a switch.
So, turns out finding a memory in the
brain
isn't all that easy.
And also, there's way more cells in your
brain
than the number of straws in a typical haystack.
But luckily, we got help from the
brain
itself.
It turned out that all we need to do is basically to let the
brain
form a memory, and then the
brain
will tell us which cells are involved in that particular memory.
SR: So what was going on in my
brain
while I was recalling the memory of an ex?
If you were to just completely ignore human ethics for a second and slice up my
brain
right now, you would see that there was an amazing number of
brain
regions that were active while recalling that memory.
Now one
brain
region that would be robustly active in particular is called the hippocampus, which for decades has been implicated in processing the kinds of memories that we hold near and dear, which also makes it an ideal target to go into and to try and find and maybe reactivate a memory.
XL: So we clipped part of this sensor, and attached that to a switch to control the cells, and we packed this switch into an engineered virus and injected that into the
brain
of the mice.
The sea of blue that you see here are densely packed
brain
cells, but the green
brain
cells, the green
brain
cells are the ones that are holding on to a specific fear memory.
It should act at the speed of the brain, in milliseconds.
SR: So what do you think, Xu? Could we use, let's say, pharmacological drugs to activate or inactivate
brain
cells?
So Steve, how about let's zap the
brain
with electricity?
SR: So electricity is pretty fast, but we probably wouldn't be able to target it to just the specific cells that hold onto a memory, and we'd probably fry the
brain.
So it looks like, hmm, indeed we need to find a better way to impact the
brain
at the speed of light.
Now to do that, first we need to trick
brain
cells to respond to laser beams.
We are trying to shoot lasers into the
brain.
Optogenetics gave us this light switch that we can use to turn
brain
cells on or off, and the name of that switch is channelrhodopsin, seen here as these green dots attached to this
brain
cell.
You can think of channelrhodopsin as a sort of light-sensitive switch that can be artificially installed in
brain
cells so that now we can use that switch to activate or inactivate the
brain
cell simply by clicking it, and in this case we click it on with pulses of light.
XL: So we attach this light-sensitive switch of channelrhodopsin to the sensor we've been talking about and inject this into the
brain.
But is there a possibility that we can actually get inside the
brain
and edit this movie clip so that we can make it different from the original?
Rather than finding a fear memory in the brain, we can start by taking our animals, and let's say we put them in a blue box like this blue box here and we find the
brain
cells that represent that blue box and we trick them to respond to pulses of light exactly like we had said before.
We can shoot light into the
brain
to reactivate the memory of the blue box.
SR: For example, one group in our lab was able to find the
brain
cells that make up a fear memory and converted them into a pleasurable memory, just like that.
It's getting more oxygen to your
brain.
It fine-tunes your
brain'
s social instincts.
Well, oxytocin doesn't only act on your
brain.
It's kind of like you have all these fancy sensors, and inside your
brain
is a little security guard.
But clearly, this is not enabled just by the
brain
of this animal, but also by his body, and it's a clear example, maybe the clearest example, of embodied intelligence, which is a kind of intelligence that all living organisms have.
You've got, of course, the human
brain
right next to healthcare, which you might expect, but also you've got video games, which is sort of adjacent, as those two spaces interface with each other.
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