Receptor
in sentence
51 examples of Receptor in a sentence
Whenever a flash of light hits the receptor, the pore opens, an electrical current is switched on, and the neuron fires electrical impulses.
And the daf-2 gene encodes a hormone
receptor.
So what you see in the picture there is a cell with a hormone
receptor
in red punching through the edge of the cell.
Okay, so what is the daf-2
receptor
telling the inside of the cell?
I just told you that, if you make a mutation in the daf-2 gene cell, that you get a
receptor
that doesn't work as well; the animal lives longer.
So that means that the normal function of this hormone
receptor
is to speed up aging.
The daf-2 hormone
receptor
is very similar to the
receptor
for the hormone insulin and IGF-1.
So after we made our discoveries with little C. elegans, people who worked on other kinds of animals started asking, if we made the same daf-2 mutation, the hormone
receptor
mutation, in other animals, will they live longer?
The
receptor
isn't working as well.
Well when the daf-2
receptor
is active, then it triggers a series of events that prevent FOXO from getting into the nucleus where the DNA is.
As well, we could characterize the fungal
receptor
receiving those signals and part of the underlying reaction occurring within the fungus and leading to its direct growth toward the plant.
So doing the screen, we discovered one mutant that took much longer than normal to calm down after the air puffs, and when we examined the gene that was affected in this mutation, it turned out to encode a dopamine
receptor.
So when we take away the dopamine
receptor
and the flies take longer to calm down, from that we infer that the normal function of this
receptor
and dopamine is to cause the flies to calm down faster after the puff.
Is that true of our dopamine
receptor
mutant flies?
Well, if you do this test on dopamine
receptor
mutant flies, they don't learn.
We take our dopamine
receptor
mutant flies and we genetically restore, or cure, the dopamine
receptor
by putting a good copy of the dopamine
receptor
gene back into the fly brain.
If we put a good copy of the dopamine
receptor
back in this elliptical structure called the central complex, the flies are no longer hyperactive, but they still can't learn.
On the other hand, if we put the
receptor
back in a different structure called the mushroom body, the learning deficit is rescued, the flies learn well, but they're still hyperactive.
Rather, it's acting to control two different functions on two different circuits, so the reason there are two things wrong with our dopamine
receptor
flies is that the same
receptor
is controlling two different functions in two different regions of the brain.
LSD and psilocybin both function like serotonin in the brain, binding directly to one type of serotonin
receptor
in particular.
We don't just have one kind of
receptor.
Synthorx is working closely with my lab, and they're interested in a protein that recognizes a certain
receptor
on the surface of human cells.
But the problem is that it also recognizes another
receptor
on the surface of those same cells, and that makes it toxic.
So could we produce a variant of that protein where the part that interacts with that second bad
receptor
is shielded, blocked by something like a big umbrella so that the protein only interacts with that first good
receptor?
When we see, it's because the energy of light stimulates a
receptor
in our eye called the retina.
The olfactory epithelium has a layer of olfactory
receptor
cells, special neurons that sense smells, like the taste buds of your nose.
As they dissolve, they bind to the olfactory
receptor
cells, which fire and send signals through the olfactory tract up to your brain.
It turns out that your brain has 40 million different olfactory
receptor
neurons, so odor A might trigger neurons 3, 427, and 988, and odor B might trigger neurons 8, 76, and 2,496,678.
This second airflow enters a region filled with highly specialized olfactory
receptor
cells, several hundred millions of them, compaired to our five million.
Several common anesthetics bind to the GABA-A
receptor
in the brain's neurons.
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