Insulin
in sentence
86 examples of Insulin in a sentence
Do you realize that we can take advantage and commandeer the machinery of a common bacterium to produce the protein of human
insulin
used to treat diabetics?
This is not like human insulin; this is the same protein that is chemically indistinguishable from what comes out of your pancreas.
The same technology that has produced the human
insulin
in bacteria can make viruses that will not only protect you against themselves, but induce immunity against other viruses.
The daf-2 hormone receptor is very similar to the receptor for the hormone
insulin
and IGF-1.
Now you've all heard of at least
insulin.
There's one called TOR, which is another nutrient sensor, like the
insulin
pathway.
And the reason is that these hormones, like the
insulin
and the IGF hormones and the TOR pathway, they're essential.
And also, there are other ways of activating FOXO that don't even involve
insulin
or IGF-1 that might even be safer.
And I recovered, thanks to the miracles of modern medicine,
insulin
and other things, and gained all my weight back and more.
You see, diabetes is an autoimmune disease where your body fights itself, and at the time people thought that somehow maybe exposure to a pathogen had triggered my immune system to fight the pathogen and then kill the cells that make
insulin.
And somehow maybe the microbial community that's in and on me got off, and then this triggered some sort of immune response and led to me killing the cells that make
insulin
in my body.
And what was remarkable about it was in the past when we think of chemical messengers within the body, we thought of complicated things like estrogen and insulin, or nerve transmission.
You can think of
insulin
as this master hormone that controls what our body does with the foods we eat, whether we burn it or store it.
Now failure to produce enough
insulin
is incompatible with life.
And
insulin
resistance, as its name suggests, is when your cells get increasingly resistant to the effect of
insulin
trying to do its job.
Once you're insulin-resistant, you're on your way to getting diabetes, which is what happens when your pancreas can't keep up with the resistance and make enough
insulin.
More importantly, I don't have
insulin
resistance.
And underlying these questions, I became almost maniacally obsessed in trying to understand the real relationship between obesity and
insulin
resistance.
Now, most researchers believe obesity is the cause of
insulin
resistance.
Logically, then, if you want to treat
insulin
resistance, you get people to lose weight, right?
What if obesity isn't the cause of
insulin
resistance at all?
You can think of
insulin
resistance as the reduced capacity of our cells to partition fuel, as I alluded to a moment ago, taking those calories that we take in and burning some appropriately and storing some appropriately.
So now, when
insulin
says to a cell, I want you to burn more energy than the cell considers safe, the cell, in effect, says, "No thanks, I'd actually rather store this energy."
So for many of us, about 75 million Americans, the appropriate response to
insulin
resistance may actually be to store it as fat, not the reverse, getting
insulin
resistance in response to getting fat.
So what I'm suggesting is maybe we have the cause and effect wrong on obesity and
insulin
resistance.
Maybe we should be asking ourselves, is it possible that
insulin
resistance causes weight gain and the diseases associated with obesity, at least in most people?
We know that 30 million obese Americans in the United States don't have
insulin
resistance.
So if you can be obese and not have
insulin
resistance, and you can be lean and have it, this suggests that obesity may just be a proxy for what's going on.
So what if we're fighting the wrong war, fighting obesity rather than
insulin
resistance?
If you ask yourself, what's a cell trying to protect itself from when it becomes
insulin
resistant, the answer probably isn't too much food.
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Related words
Resistance
Obesity
Diabetes
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