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Mutation in sentence

128 examples of Mutation in a sentence

See, for four billion years, what lived and died on this planet depended on two principles: on natural selection and random mutation.
And what we've done is created this completely parallel evolutionary system where we are practicing unnatural selection and non-random mutation.
How about this random mutation stuff?
Well, this is random mutation.
And he had a random mutation that gave him six fingers on each hand, which turns out to be really useful if you're a pitcher.
How about non-random mutation?
A non-random mutation is beer.
For a handful of people on the planet who carry a rare inherited genetic mutation, sleeplessness is a daily reality.
If you're like Alice in "Still Alice," you've inherited a rare genetic mutation that cranks out amyloid beta, and this alone will tip your scale arm to the ground.
Those are then selected by the algorithm, reproduced with mutation and recombinations to introduce sex as well.
A small mutation can take a two-wing fly and make it a four-wing fly.
It shows up at places like MIT, and then a mutation happens.
But every now and then, a point mutation disrupts an important capability in a cell or causes a cell to misbehave in harmful ways.
If that mutation were inherited from your parents or occurred early enough in your development, then the result would be that many or all of your cells contain this harmful mutation.
Led by Nicole Gaudelli, a former post doc in the lab, we set out to develop this second class of base editor, which, in theory, could correct up to almost half of pathogenic point mutations, including that mutation that causes the rapid-aging disease progeria.
While many of these diseases are thought to be treatable by correcting the underlying mutation in even a modest fraction of cells in an organ, delivering molecular machines like base editors into cells in a human being can be challenging.
But in sickle cell disease, a single genetic mutation alters the structure of hemoglobin.
Perhaps what’s most surprising about this malignant mutation is that it originally evolved as a beneficial adaptation.
Researchers have been able to trace the origins of the sickle cell mutation to regions historically ravaged by a tropical disease called malaria.
And if a child inherits a copy of the mutation from only one parent, there will be just enough abnormal hemoglobin to make life difficult for the malaria parasite, while most of their red blood cells retain their normal shape and function.
In regions rife with this parasite, sickle cell mutation offered a serious evolutionary advantage.
But as the adaptation flourished, it became clear that inheriting the mutation from both parents resulted in sickle-cell anemia.
And this mutation still plays a key role in Africa, where more than 90% of malaria infections occur worldwide.
It will adapt to its environment; it's a durable mutation.
We have a strong association between the presence of this virus and a genetic mutation that's been linked to cancer.
Two years ago the migrating birds had a multiple event where thousands died because of a mutation occurring in the virus, which made the species range broaden dramatically.
What this means is that one of the two copies of chromosome number 15 that I have in each of my cells has a genetic mutation.
Because I still have one normal copy of this gene, the mutation doesn't affect me.
But if a baby inherits this mutation from both parents, if both copies of this particular gene don't function properly, it results in Tay-Sachs, an incurable disease that progressively shuts down the central nervous system and causes death by age five.
I knew that my husband, whose ancestry isn't Eastern European Jewish like mine, had a very low likelihood of also being a carrier for the Tay-Sachs mutation.
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