Mutation
in sentence
128 examples of Mutation in a sentence
While the frequency of heterozygotes, individuals who have one normal copy of the gene and one mutated copy, is about one out of 27 people among Jews of Ashkenazi descent, like me, in most populations, only one in about 300 people carry the Tay-Sachs
mutation.
The unusually high rate of the Tay-Sachs
mutation
in Ashkenazi Jews today may relate to advantages the
mutation
gave this population in the past.
Now I'm sure some of you are thinking, "I'm sorry, did you just suggest that this disease-causing
mutation
had beneficial effects?"
Certainly not for individuals who inherited two copies of the
mutation
and had Tay-Sachs.
By changing the shape of a person's red blood cells, the sickle cell
mutation
confers protection against malaria.
People with the
mutation
aren't less likely to get bitten by the mosquitoes that transmit the disease, but they are less likely to get sick or die as a result.
But the unusual prevalence of the Tay-Sachs
mutation
in Ashkenazi populations may be another example of heterozygote advantage.
The data hinted that the persistence of the Tay-Sachs
mutation
among Ashkenazi Jews might be explained by the benefits of being a carrier in an environment where tuberculosis was prevalent.
Even if the Tay-Sachs
mutation
persisted because carriers were more likely to survive, reproduce and pass on their genetic material, why did this resistance mechanism proliferate among the Ashkenazi population in particular?
And while it was unclear in the 1970s or '80s how exactly the Tay-Sachs
mutation
offered protection against TB, recent work has identified how the
mutation
increases cellular defenses against the bacterium.
This explains why a
mutation
like the one that causes Huntington's disease, another degenerative neurological disorder, hasn't been eliminated by natural selection.
The
mutation'
s detrimental effects usually don't appear until after the typical age of reproduction, when affected individuals have already passed on their genes.
This makes coronaviruses much more stable, with a slower
mutation
rate, than other RNA viruses.
While this may sound formidable, the slow
mutation
rate is actually a promising sign when it comes to disarming them.
The slower
mutation
rate of coronaviruses means our immune systems, drugs, and vaccines might be able to recognize them for longer after infection, and therefore protect us better.
The website says, "If you look, there's an individual mutation, and maybe a second, and maybe a third, and that is cancer."
And when they were subject to the plague, most people didn't survive, but those who survived had a
mutation
on the CCR5 receptor.
And that
mutation
was passed on to their kids because they're the ones that survived, so there was a great deal of population pressure.
In Africa, because you didn't have these cities, you didn't have that CCR5 population pressure
mutation.
Sergio Martino's film takes ideas such as mutation, greed and adventure and moulds it into one slightly compelling film, which makes up for what it's lacks in coherency and logic with a load of mostly intriguing ideas.
I agree with the other reviewers that the children in the movie are an unfortunate
mutation
that now plagues us nightly in sit-coms and the dialogue is stilted and preachy.
A murdered illegal immigrant, fished out of the bay, is found to be infected with pneumonic plague, a deadly air-borne
mutation
of bubonic plague, which is transmitted from human-to-human and, untreated, has a mortality rate that approaches 100%.
A laboratory experiment goes terribly wrong leaving a scientist, Professor Adams, radioactively infected with a horrible
mutation
effecting his whole body.
I know, I know, cannibalism is a social behavior, not a pathogen, and the movie knows it, too, so some brief lip service is paid to a theory of psychic
mutation
which is never really explained and immediately forgotten.
Has anyone noticed the monster here is a genetic mutation, thereby negating the title?
Among the other survivors are Ralph Richardson (O Lucky Man!) as Lord Fortnum of Alamein, who isn't looking forward to his impending
mutation
into a bed sitting room.
First, most emerging infectious diseases are zoonoses, meaning that they start in animal populations, sometimes with a genetic
mutation
that enables the jump to humans.
Yet each breakthrough inevitably leads to the pathogen’s mutation, rendering previous treatments less effective.
So, is the world ready for Ebola, a newly lethal influenza, a
mutation
of HIV that could speed the transfer of the disease, or the development of new multi-drug-resistant strains of malaria or other pathogens?
Microscopic pigment granules produced by skin pigment cells aggregate around the cell's nucleus to shield the DNA from the marauding rays and prevent
mutation.
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