Genomes in sentence

92 examples of Genomes in a sentence

Now, although that might sound impressive, in some ways it's a little bit problematic as a medical test, because you can probably tell which of these people is obese without knowing anything about their gut microbes, but it turns out that even if we sequence their complete genomes and had all their human DNA, we could only predict which one was obese with about 60 percent accuracy.

We're so lucky to be born in the time that sequencing genomes is a routine activity, and the brilliant folks at Synthetic Genomics are able to zero in on the pig genome, find exactly the genes that are problematic, and fix them.

A few years ago, with my colleague, Emmanuelle Charpentier, I invented a new technology for editing genomes.

And we also worked around the clock doing shift work, day after day, and we quickly generated 99 genomes of the Ebola virus.

We could actually take these 99 different viruses, look at them and compare them, and we could see, actually, compared to three genomes that had been previously published from Guinea, we could show that the outbreak emerged in Guinea months before, once into the human population, and from there had been transmitting from human to human.

Just like we have different colored eyes and hair, we metabolize drugs differently based on the variation in our genomes.

Traditionally, genomes are sequenced in laboratories.

But what if you could sequence genomes on the fly?

Another is looking to use genetic tools to cut the HIV DNA out of cells genomes altogether.

The different genomes of each species represent different survival strategies.

We probably read more than half of the prior animal genomes in the world.

This is the reason why we need to read those genomes.

It's a competition we're holding, the second X PRIZE, for the first team to sequence 100 human genomes in 10 days.

But close analysis of the genomes and coat patterns of modern cats tells us that unlike dogs, which have undergone centuries of selective breeding, modern cats are genetically very similar to ancient cats.

This is exactly analogous to the question, what's the smallest program I can write that will act exactly like Microsoft Word? (Laughter) And just as he's writing, you know, bacteria that will be smaller, he's writing genomes that will work, we could write smaller programs that would do what Microsoft Word does.

Well, that's what you're beginning to see because you have so many medical records, because you have so much data about people: you've got their genomes, you've got their viromes, you've got their microbiomes.

We have genomes, we have DNA, DNA is transcripted into RNA, RNA translates that into a protein, and that's how we come to be.

They have big genomes, they have DNA, they transcript it into RNA, but now something dramatically different happens.

You probably hear about genomes these days.

So, we are now able to read genomes.

And if you think about the computer industry and how we've gone from big computers to little ones and how they get more powerful and faster all the time, the same thing is happening with gene sequencing now: we are on the cusp of being able to sequence human genomes for about 5,000 dollars in about an hour or a half-hour; you will see that happen in the next five years.

So, what can we do with genomes now that we can read them, now that we're starting to have the book of life?

We are now not just reading genomes; we are writing them.

But we've also discovered, when it comes to plants, in plants, as much as we understand and are starting to understand their genomes, it is the ecosystem around them, it is the microbes that live in their root systems, that have just as much impact on the character of those plants as the metabolic pathways of the plants themselves.

We use CAT scans, we use isotopes, we use genomes, we use robots, we use mathematical simulations and all kinds of analytics.

So in the last decade, a large number of genomes have been added: most human pathogens, a couple of plants, several insects and several mammals, including the human genome.

Genomics at this stage of the thinking from a little over 10 years ago was, by the end of this year, we might have between three and five genomes sequenced; it's on the order of several hundred.

We just got a grant from the Gordon and Betty Moore Foundation to sequence 130 genomes this year, as a side project from environmental organisms.

We also tried to take a more directly intellectual approach with the genomes of 13 related organisms, and we tried to compare all of those, to see what they had in common.

So we think that we can expand or contract genomes, depending on your point of view here, to maybe 300 to 400 genes from the minimal of 500.

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