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Genomes in sentence

92 examples of Genomes in a sentence

He actually was the first person to clone a dog, which is a very difficult thing to do, because dog genomes are very plastic.
What I want to talk to you about is what we can learn from studying the genomes of living people and extinct humans.
But before doing that, I just briefly want to remind you about what you already know: that our genomes, our genetic material, are stored in almost all cells in our bodies in chromosomes in the form of DNA, which is this famous double-helical molecule.
And we will find that the two genomes in me, or one genome of mine we want to use, will have about three million differences in the order of that.
And you can begin to compare it to the genomes of people who live today.
And the way to ask that question is to look at the Neanderthal that comes from Southern Europe and compare it to genomes of people who live today.
So we then look to do this with pairs of individuals, starting with two Africans, looking at the two African genomes, finding places where they differ from each other, and in each case ask: What is a Neanderthal like?
So from studying these genomes of extinct humans, we're beginning to arrive at a picture of what the world looked like when modern humans started coming out of Africa.
So to sum up, what have we learned from studying genomes of present day humans and extinct humans?
So the worldwide capacity to sequence human genomes is something like 50,000 to 100,000 human genomes this year.
And he took skin cells, healthy skin and cancerous bone marrow, and sequenced the whole genomes of both of them in a couple of weeks, no big deal.
What I'd like you to consider is: What does it mean when these dots don't represent the individual bases of your genome, but they connect to genomes all across the planet?
Now we, as humans, we store our information as DNA in our genomes and we pass this information on to our offspring.
So if we zoom in to an even deeper level, all of those proteins are encoded by our genomes.
They look at their entire genomes, and they try to find hot spots of activity that are linked causally to genes.
But the fact is our genomes are greater than 99 percent similar.
And as it continues, one of the things that's going to happen this year is we're going to discover the first 10,000 human genomes, because it's gotten cheap enough to do the gene sequencing.
So now we're able to gather data about our genomes, but, as we saw earlier, our genomes aren't dispositive.
And more importantly, we're able to gather information about our choices, because it turns out that what we think of as our health is more like the interaction of our bodies, our genomes, our choices and our environment.
The sequence of events: he'll put together the genomes of the band-tailed pigeon and the passenger pigeon, he'll take the techniques of George Church and get passenger pigeon DNA, the techniques of Robert Lanza and Michael McGrew, get that DNA into chicken gonads, and out of the chicken gonads get passenger pigeon eggs, squabs, and now you're getting a population of passenger pigeons.
They're going to work on the genomes of the passenger pigeon and the band-tailed pigeon.
With advances in ancient DNA technology, we can actually now start to begin to sequence the genomes of those other extinct mammoth forms that I mentioned, and I just wanted to talk about two of them, the woolly and the Columbian mammoth, both of which were living very close to each other during glacial peaks, so when the glaciers were massive in North America, the woollies were pushed into these subglacial ecotones, and came into contact with the relatives living to the south, and there they shared refugia, and a little bit more than the refugia, it turns out.
And about that time, it became possible to sequence their genomes and really look under the hood and look at their genetic makeup.
And we've been able to sequence the genomes of cultures that we have, but also recently, using flow cytometry, we can isolate individual cells from the wild and sequence their individual genomes, and now we've sequenced hundreds of Prochlorococcus.
Over the past 15 years or so, my teams have been developing the technology for stitching together those short pieces of DNA into complete bacterial genomes.
This genome transplantation technology then paved the way for the booting-up of genomes written by scientists and not by Mother Nature.
Ever since the first bacterial genome was sequenced, back in 1995, thousands more whole bacterial genomes have been sequenced and stored in computer databases.
There are hundreds of places in our genomes that shape risk for brain illnesses, and any one of them could lead us to the next molecular insight about a molecule that matters.
And we're developing a way to test in a single tube how cells with hundreds of different people's genomes respond differently to the same stimulus.
This is the first talk I've given about this expedition, and while we weren't sequencing genomes or building space telescopes, this is a story about giving everything we had to achieve something that hadn't been done before.
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