Trials
in sentence
727 examples of Trials in a sentence
Now today, many clinical
trials
are using different kinds of stem cells for heart disease.
As we speak, there are 117 or so clinical
trials
researching the use of stem cells for liver diseases.
There are 170 clinical
trials
investigating the role of stem cells in heart disease.
Still in clinical trials, but imagine when we can connect these, for example, to the amazing bionic limb, such as the DEKA Arm, built by Dean Kamen and colleagues, which has 17 degrees of motion and freedom, and can allow the person who's lost a limb to have much higher dexterity or control than they've had in the past.
We've been using adult stem cells in clinical
trials
for about 15 years to approach a whole range of topics, particularly cardiovascular disease.
I'm not even telling you the story because I think we should be running more carefully controlled randomized
trials
in all aspects of public policy, although I think that would also be completely awesome.
You're killing people with your clinical
trials.
On some trials, we'll ask them to pay attention to the face.
On those
trials
they were told just to withhold the response.
Trials
are old; the first one was in the Bible, Daniel 1:12.
So we know that our beliefs and expectations can be manipulated, which is why we do
trials
where we control against a placebo, where one half of the people get the real treatment, and the other half get placebo.
So firstly,
trials
against placebo: everybody thinks a trial should be a comparison of your new drug against placebo.
And yet, repeatedly, you consistently see people doing
trials
still against placebo.
So people set about doing
trials
of the new drugs against the old drugs.
Everybody wanted to show their drug was better than risperidone, so you see
trials
comparing new antipsychotic drugs against risperidone at eight milligrams a day.
And so it's no surprise that overall, industry-funded
trials
are four times more likely to give a positive result than independently sponsored
trials.
A funnel plot is a very clever way of spotting if small negative
trials
have disappeared, have gone missing in action.
This is a graph of all of the
trials
done on a particular treatment.
As you go up, those are bigger trials, so they've got less error; they're less likely to be randomly false positives or negatives.
The big
trials
are closer to the true answer.
If there is publication bias, if small negative
trials
have gone missing in action, you can see it on one of these graphs.
So you see here that the small negative
trials
that should be on the bottom left have disappeared.
Unfortunately, it turned out, that many of these
trials
were withheld.
In fact, 76 percent of all of the
trials
that were done on this drug were withheld from doctors and patients.
We've completed, now, clinical
trials
in four mouse models of this disease.
And it's not just because of regulation; it's because of the amount of money needed under the current evidence-based medicine and the size of
trials
and so on to make it happen.
We have more
trials
planned for lung cancer, pancreatic cancer, ovarian cancer and breast cancer.
But on some trials, we could change the shape and size of the environment like we did with the place cell.
Some of these lawyers were successful; they managed to get new
trials
for their clients.
Well, here I can't help but think of the groundbreaking clinical
trials
recently conducted at East Carolina University that showed that online games can outperform pharmaceuticals for treating clinical anxiety and depression.
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