Opioids
in sentence
26 examples of Opioids in a sentence
Hardly ever would we offer people what they desperately need to survive: a safe prescription for
opioids.
There is a kind of perfect storm around
opioids.
It is estimated that two million Americans are daily opioid users, and over 60 million people received at least one prescription for
opioids
last year.
And so inside the library, it is routine to see people visibly intoxicated on opioids: eyes closing, body swaying slowly.
I don't know how many of you have witnessed an overdose on opioids, but it's horrific because you know the gasping for air, the loss of color in someone's face, is a timer running down on the chances of this person surviving.
Common intravenous agents include sedatives, like propofol, which induce unconsciousness, and opioids, like fentanyl, which reduce pain.
Many of the drugs I prescribe are drugs like
opioids
or benzodiazepines which can be dangerous if overused.
We're wired for dangers that are immediate, that are physical, that are imminent, and so our body goes into an incredible reaction where endogenous
opioids
come in.
Brain studies have shown that the withdrawal of romantic love activates the same mechanisms in our brain that get activated when addicts are withdrawing from substances like cocaine or
opioids.
Likewise, for chronic non-cancer pain, there is virtually no evidence to support the long-term use of high doses of opioids, which often do more harm than good.
Citizens of affluent countries are used to hearing that
opioids
are too easy to get.
In the United States, the quantity of available
opioids
– that is, drugs with morphine-like effects on pain – is more than three times what patients in need of palliative care require.
People in the US suffer from over-prescription of
opioids
while people in developing countries are often suffering because of under-prescription.
Although it is generally the poor who lack access to opioids, the main problem is not, for once, cost: doses of immediate-release, off-patent morphine cost just a few cents each.
The total cost of closing the “pain gap” and providing all the necessary
opioids
would be just $145 million a year at the lowest retail prices (unfairly,
opioids
are often more expensive for poorer countries than richer ones).
The misplaced fear that allowing
opioids
to be used in hospitals will fuel addiction and crime in the community has led to tight restrictions on their use, and clinicians are not trained to provide them when they are needed.
While
opioids
can be harmful and addictive, as America’s current crisis demonstrates, the fact that something can be dangerous is not sufficient reason to impose extreme restrictions on its clinical use.
But if her story is true, she is also a victim of the excessively tight restrictions on
opioids
that prevented her boyfriend from obtaining tramadol legally.
Then they entice doctors with inducements and giveaways – including trips, toys, fishing hats, and, in one case, a music CD called “Get in the Swing with OxyContin” (one of the most popular opioids) – to prescribe them.
For example, when patients experience pain relief from placebos, the brain releases endogenous
opioids
and/or CB1 cannabinoids – the very same mechanisms that mediate pain relief derived from pharmaceutical treatments.
That strategy includes the Food and Drug Administration’s
Opioids
Action Plan, which aims to reexamine the underlying risk-benefit paradigm for
opioids
and to reduce the number of prescriptions for opioid painkillers through education programs.
According to the HHS, an estimated 130 or more people died from opioid-related drug overdoses each day in 2016 and 2017 – a period during which two million people misused prescription
opioids
for the first time.
Figures from the US Centers for Disease Control and Prevention show that from 1999 to 2017, almost 218,000 people died from overdoses related to prescription
opioids.
The drug most responsible for this catastrophic abuse of prescription
opioids
is OxyContin, produced by Purdue Pharma LP, which is reported to have made more than $31 billion from OxyContin sales.
The dominance of OxyContin among prescription
opioids
was not due to any inherent advantages; several carefully controlled trials concluded that it had none.
That would allow businesses to pollute the air more, get more Americans hooked on opioids, entice more children to eat their diabetes-inducing foods, and engage in the sort of financial shenanigans that brought on the 2008 crisis.
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