Genome
in sentence
369 examples of Genome in a sentence
Since then, the costs of mapping the
genome
have come down.
Now, in the days when mapping a
genome
cost millions, or even tens of thousands, it was basically a research enterprise.
But when the
genome
can be mapped for 100 bucks, 99 dollars while you wait, then what happens is, it becomes retail.
You go the doctor with a cold, and if he or she hasn't done it already, the first thing they do is map your genome, at which point what they're now doing is not starting from some abstract knowledge of genomic medicine and trying to work out how it applies to you, but they're starting from your particular
genome.
Think about the
genome.
That's four times the size of the human
genome.
Unlike your own genome, it's a living, breathing thing, and there's a broad front of research happening right now to better understand how we can restore our microbiomes when something goes wrong, using diet, using live microbes.
OK, a
genome
is a complete set of DNA within an organism.
The largest
genome
that we constructed contained over one million letters.
Once we chemically synthesized the complete bacterial genome, our next challenge was to find a way to convert it into a free-living, self-replicating cell.
Our approach was to think of the
genome
as the operating system of the cell, with the cell containing the hardware necessary to boot up the
genome.
Through a lot of trial and error, we developed a procedure where we could reprogram cells and even convert one bacterial species into another, by replacing the
genome
of one cell with that of another.
This
genome
transplantation technology then paved the way for the booting-up of genomes written by scientists and not by Mother Nature.
Ever since the first bacterial
genome
was sequenced, back in 1995, thousands more whole bacterial genomes have been sequenced and stored in computer databases.
Our synthetic cell work was the proof of concept that we could reverse this process: pull a complete bacterial
genome
sequence out of the computer and convert that information into a free-living, self-replicating cell, with all of the expected characteristics of the species that we constructed.
We decoded our
genome.
It had been known for several years that the human
genome'
s largest influence on risk of schizophrenia comes from a part of the
genome
that encodes many of the molecules in our immune system.
Technology has brought us so much: the moon landing, the Internet, the ability to sequence the human
genome.
We wanted to take out all 62 copies of the PERV virus from the pig genome, but at the time, it was nearly mission impossible.
What it means that the three pounds of microbes that you carry around with you may be more important for some health conditions than every single gene in your
genome.
He took a snippet of viral DNA and he inserted it into the papaya
genome.
In the genetic approach, scientists cut the gene out of the bacteria and insert it directly into the eggplant
genome.
So we've teamed up with the decoder of the human genome, Craig Venter, and the company he founded with Peter Diamandis, the founder of the X Prize, to genetically modify the pig
genome
so that the pig's organs will not be rejected by the human body and thereby to create an unlimited supply of transplantable organs.
We're so lucky to be born in the time that sequencing genomes is a routine activity, and the brilliant folks at Synthetic Genomics are able to zero in on the pig genome, find exactly the genes that are problematic, and fix them.
We've been digitizing it now for almost 20 years; when we sequenced the human genome, it was going from the analog world of biology into the digital world of the computer.
This is the map of a small organism, Mycoplasma genitalium, that has the smallest
genome
for a species that can self-replicate in the laboratory, and we've been trying to just see if we can come up with an even smaller
genome.
And this was our first attempt, starting with the digital information of the
genome
of phi X174.
When we first sequenced this
genome
in 1995, the standard of accuracy was one error per 10,000 base pairs.
There's a lot of talk in technologyland about the personalization of medicine, that we have all this data and that medical treatments of the future will be for you specifically, your genome, your current context.
That's because the gene is such a dominant metaphor, again, to use that same word, in medicine today, that we think the
genome
will drive the personalization of medicine.
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