Genome
in sentence
369 examples of Genome in a sentence
In a biohacker space, you can analyze your
genome
for mutations.
Another thing we can't see is the human
genome.
And this is increasingly peculiar, because about 20 years ago when they started delving into the genome, they thought it would probably contain around 100 thousand genes.
We now think there are likely to be just over 20 thousand genes in the human
genome.
Inside every cell in your body lies your
genome.
Your
genome
is made up of your DNA, your DNA codes for proteins that enable you to function and interact and be as you are.
Now since the new advancements in modern molecular technologies, it is now possible for us to sequence our own
genome
in a very rapid time and at a very, very reduced cost.
Now when we've been doing this, we've realized that there's variations within our
genome.
And so therefore, if you look at the same region of a
genome
in many mammals that have been evolutionarily distant from each other and are also ecologically divergent, you will get a better understanding of what the evolutionary prior of that site is, i.e., if it is important for the mammal to function, for its survival, it will be the same in all of those different lineages, species, taxa.
So in this case here, if all the mammals that we look at have a yellow-type
genome
at that site, it probably suggests that purple is bad.
So say, for example, the region of the
genome
that I was looking at was a region that's important for vision.
This is where we're going to go, and as I said before, I really believe that the secret of everlasting youth lies within the bat
genome.
So how could the secret of everlasting youth actually lie within the bat
genome?
It's DNA which is pretty badly fragmented, but with good techniques now, you can basically reassemble the whole
genome.
Then the question is, can you reassemble, with that genome, the whole bird?
The passenger pigeon has 1.3 billion base pairs in its
genome.
So this is a form of synthetic hybridization of the
genome
of an extinct species with the
genome
of its closest living relative.
The aurochs is the ancestor of all domestic cattle, and so basically its
genome
is alive, it's just unevenly distributed.
Well, one way to go faster is to take advantage of technology, and a very important technology that we depend on for all of this is the human genome, the ability to be able to look at a chromosome, to unzip it, to pull out all the DNA, and to be able to then read out the letters in that DNA code, the A's, C's, G's and T's that are our instruction book and the instruction book for all living things, and the cost of doing this, which used to be in the hundreds of millions of dollars, has in the course of the last 10 years fallen faster than Moore's Law, down to the point where it is less than 10,000 dollars today to have your
genome
sequenced, or mine, and we're headed for the $1,000
genome
fairly soon.
But the second example I want to give you is, I happened to be an early guinea pig, and I got very lucky to have my whole
genome
sequenced.
If you had asked me 10 years ago whether or not we would ever be able to sequence the
genome
of extinct animals, I would have told you, it's unlikely.
Well, the mammoth
genome
is almost at full completion, and we know that it's actually really big.
So a hominid
genome
is about three billion base pairs, but an elephant and mammoth
genome
is about two billion base pairs larger, and most of that is composed of small, repetitive DNAs that make it very difficult to actually re-jig the entire structure of the
genome.
So having this information allows us to answer one of the interesting relationship questions between mammoths and their living relatives, the African and the Asian elephant, all of which shared an ancestor seven million years ago, but the
genome
of the mammoth shows it to share a most recent common ancestor with Asian elephants about six million years ago, so slightly closer to the Asian elephant.
So that means that we can actually take Asian elephant chromosomes, modify them into all those positions we've actually now been able to discriminate with the mammoth genome, we can put that into an enucleated cell, differentiate that into a stem cell, subsequently differentiate that maybe into a sperm, artificially inseminate an Asian elephant egg, and over a long and arduous procedure, actually bring back something that looks like this.
That's a big chunk of the global
genome
gone.
They took some of this same pickled thylacine DNA and they spliced it into a mouse genome, but they put a tag on it so that anything that this thylacine DNA produced would appear blue-green in the mouse baby.
And that tells us if we can get that
genome
back together, get it into a live cell, it's going to produce thylacine stuff.
We can also envision a romantic use of the
genome.
The first human genome, that of James Watson, was mapped as the culmination of the Human
Genome
Project in the year 2000, and it took about 200 million dollars and about 10 years of work to map just one person's genomic makeup.
Back
Next
Related words
Human
About
Genes
First
Sequencing
Sequence
Years
Which
Would
There
Sequenced
Genetic
Billion
Entire
Editing
Today
Scientists
Million
Three
Their