Genome
in sentence
369 examples of Genome in a sentence
But of course the
genome
is just the bottom of a long chain of being, as it were.
The opportunity to do this kind of
genome
editing also raises various ethical issues that we have to consider, because this technology can be employed not only in adult cells, but also in the embryos of organisms, including our own species.
We can think of older
genome
engineering technologies as similar to having to rewire your computer each time you want to run a new piece of software, whereas the CRISPR technology is like software for the genome, we can program it easily, using these little bits of RNA.
Imagine that these white mice differ from their pigmented litter-mates by just a tiny change at one gene in the entire genome, and they're otherwise completely normal.
I think that in the end, this technology will be used for human
genome
engineering, but I think to do that without careful consideration and discussion of the risks and potential complications would not be responsible.
Allowing patent holders, often private companies, to lock up stretches of the human
genome
was harming patients.
You remember when the map of the human
genome
was unveiled at a White House ceremony in June 2000?
President Bill Clinton famously declared, "I believe one of the great truths to emerge from this triumphant expedition inside the human
genome
is that in genetic terms, human beings, regardless of race, are more than 99.9 percent the same."
Not the man in the flesh, but for the first time in history, this is the
genome
of a specific human, printed page-by-page, letter-by-letter: 262,000 pages of information, 450 kilograms, shipped from the United States to Canada thanks to Bruno Bowden, Lulu.com, a start-up, did everything.
So, one of the things that we use a lot to recognize people will never be written in the
genome.
Basically, there's a protein that acts like a scissors and cuts the DNA, and there's an RNA molecule that directs the scissors to any point on the
genome
you want.
Here's an image of your classic
genome
sequencer.
What if you could fit a
genome
sequencer in your pocket?
This nanopore-based sequencer is one 10,000th the size of your traditional
genome
sequencer.
It allows us to de-black box
genome
sequencing technology development in a way that's immersive and collaborative, activating and empowering indigenous communities ... as citizen scientists.
100 years later in Kalaupapa, we now have the technology to sequence leprosy bacteria in real time, using mobile
genome
sequencers, remote access to the Internet and cloud computation.
Preserving the
genome
of these fungi in the old-growth forest I think is absolutely critical for human health.
If you're trying to CRISPR a genome, the first thing that you have to do is damage the DNA.
The guide RNA and the Cas9 protein complex together go bouncing along the genome, and when they find a spot where the guide RNA matches, then it inserts between the two strands of the double helix, it rips them apart, that triggers the Cas9 protein to cut, and all of a sudden, you've got a cell that's in total panic because now it's got a piece of DNA that's broken.
And now mind you, in a diploid organism like people, we've got one copy of our
genome
from our mom and one from our dad, so if one gets damaged, it can use the other chromosome to repair it.
The repair is made, and now the
genome
is safe again.
I'm starting to get emails from people that say stuff like, "Hey, can I come to your open night and, like, maybe use CRISPR and engineer my genome?"
Now the other thing is, we don't really know that much about how to make a particular thing happen by changing particular spots in the
genome.
And over the last few weeks, George Church has been in the news a lot because he's been talking about taking one of these programmable cells and inserting an entire human
genome
into that cell.
And once you can insert an entire human
genome
into a cell, then you begin to ask the question, would you want to enhance any of that
genome?
We can map the entire
genome.
We would map the methylation state, and again, you see the green genes becoming red as stress increases, the red genes becoming green as stress increases, an entire rearrangement of the
genome
in response to stress.
Their genes are re-marked in a different way, and when the cue comes, their
genome
is ready to develop this addictive phenotype.
HIV is a retrovirus, which means it can write its genetic code into the
genome
of infected cells, co-opting them into making more copies of itself.
The most commonly prescribed ones prevent the viral
genome
from being copied and incorporated into a host cell's DNA.
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About
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There
Sequenced
Genetic
Billion
Entire
Editing
Today
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Three
Their