Genes in sentence

802 examples of Genes in a sentence

We also get to see areas that no one has ever looked at before, and we see these genes turned on there.

Most of you are probably familiar with genome-wide association studies in the form of people covering in the news saying, "Scientists have recently discovered the gene or genes which affect X."

They look at their entire genomes, and they try to find hot spots of activity that are linked causally to genes.

But what you get out of such an exercise is simply a list of genes.

And those genes are interesting, but they're very subtle.

These are things where genes are turned on in an individual cell type.

These are two genes that we found as good examples.

And so what you're looking at here in donor one and donor four, which are the exceptions to the other two, that genes are being turned on in a very specific subset of cells.

Now these animals are different from one another, because they have different genes.

So that suggests that somewhere in these genes, somewhere in the DNA, are genes for aging, genes that allow them to have different lifespans.

So if there are genes like that, then you can imagine that, if you could change one of the genes in an experiment, an aging gene, maybe you could slow down aging and extend lifespan.

And if you could do that, then you could find the genes for aging.

So we've set out to look for genes that control aging.

So we started to change genes at random, looking for long-lived animals.

Well as you know, genes, which are part of the DNA, they're instructions to make a protein that does something.

It says that aging is subject to control by the genes, and specifically by hormones.

Well it turns out that in the daf-2 mutants, a whole lot of genes are switched on in the DNA that encode proteins that protect the cells and the tissues, and repair damage.

There are lots of genes actually that bind on FOXO.

So FOXO turns on a lot of genes.

DNA repair genes are more active in these animals.

And many of these different genes, we've shown, actually contribute to the long lifespan of the daf-2 mutant.

So it can't turn the genes on.

So it activates FOXO, FOXO goes to the DNA, and that triggers the expression of these genes that improves the ability of the cell to protect itself and repair itself.

We all have FOXO genes, but we don't all have exactly the same form of the FOXO gene.

And each one of these stars represents a population where scientists have asked, "Okay, are there differences in the type of FOXO genes among people who live a really long time?" and there are.

We don't know the details of how this works, but we do know then that FOXO genes can impact the lifespan of people.

Although you're looking for a drug that can solve aging in old men like me, what you could do now pretty well in the lab, if you were allowed ethically, is start a human life from scratch with altered genes that would make it live for a lot longer?

CK: Ah, so the kinds of drugs I was talking about would not change the genes, they would just bind to the protein itself and change its activity.

You could change the genes in principle.

The fact we see here is the vehicle for our genes, and therefore we love it.

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