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Fibrosis in sentence

20 examples of Fibrosis in a sentence

Cystic fibrosis is an example of a disease where you just have a bad ingredient and you have a disease, and we can actually make a direct correspondence between the ingredient and the disease.
One that has just happened in the last few months is the successful approval of a drug for cystic fibrosis.
Cystic fibrosis had its molecular cause discovered in 1989 by my group working with another group in Toronto, discovering what the mutation was in a particular gene on chromosome 7.
That's Danny Bessette, 23 years later, because this is the year, and it's also the year where Danny got married, where we have, for the first time, the approval by the FDA of a drug that precisely targets the defect in cystic fibrosis based upon all this molecular understanding.
The bad news is, this drug doesn't actually treat all cases of cystic fibrosis, and it won't work for Danny, and we're still waiting for that next generation to help him.
Cilia and the clearance of mucus are also involved in awful diseases like cystic fibrosis.
The only cure for pulmonary hypertension, pulmonary fibrosis, cystic fibrosis, emphysema, COPD, what Leonard Nimoy just died of, is a lung transplant, but sadly, there are only enough available lungs for 2,000 people in the U.S. a year to get a lung transplant, whereas nearly a half million people a year die of end-stage lung failure.
So if we were able to program the CRISPR technology to make a break in DNA at the position at or near a mutation causing cystic fibrosis, for example, we could trigger cells to repair that mutation.
Wilson has termed the age of gene circumvention, during which we remedy our genetic defects like cystic fibrosis or muscular dystrophy with temporary external supplements.
The ability to fix DNA errors means that CRISPR could potentially create new treatments for diseases linked to specific genetic errors, like cystic fibrosis or sickle cell anemia.
Or, unless if you're passing on a cystic fibrosis gene, in which case, you don't just want to redesign yourself, you want to redesign your children and their children.
Both procedures are routinely offered to pregnant women 35 years and over to diagnose chromosomal abnormalities such as Down's syndrome, or to screen for cystic fibrosis, sickle cell disease, or Tay Sachs disease.
It has enabled the development of vaccines against infectious diseases and drugs that treat non-infectious illnesses like diabetes, cancer, cystic fibrosis, psoriasis, rheumatoid arthritis, and some genetic disorders.
But it is widely known that certain mutations can run in families, increasing dramatically the risks of certain diseases – for example, breast cancer, sickle-cell anemia, and cystic fibrosis.
Moreover, biomedical research firms are abandoning certain diseases in order to avoid the large-scale trials that they require, focusing instead on “orphan diseases” like cystic fibrosis, which demand smaller clinical trials that have a higher probability of success, leading to drugs that can cost more than $100,000 annually per patient.
The world is plagued with hereditary diseases that cause very real misery: sickle cell anemia, hemophilia, type 1 diabetes, cystic fibrosis, mitochondrial diseases, polycystic kidney disease, Tay-Sachs disease, Canavan disease, mucopolysaccharidoses, some forms of breast, prostate, and colon cancer – the list goes on.
Available data on the incidence of cystic fibrosis, the most important hereditary lung disease, indicate a range of between five and ten per 100,000.
These include lung, liver, and gastric cancers, as well as other liver diseases, such as chronic hepatitis B, liver fibrosis, and cirrhosis.
The protective suits that specially-trained people are legally required to wear in the European Union or the US when demolishing, rebuilding, or repairing any building containing asbestos underscore the risk of pulmonary fibrosis and lung cancer for Lebanese who inhale dust from bombed-out houses and offices.
Sickle cell anemia, Ashkenazi genetic diseases, and cystic fibrosis are just three examples of the many diseases with population-specific correlations.