Clinical
in sentence
550 examples of Clinical in a sentence
A series of recent
clinical
studies suggest that among patients who haven't yet developed Alzheimer's disease, worsening sleep quality and sleep duration are associated with a greater amount of amyloid-beta building up in the brain, and while it's important to point out that these studies don't prove that lack of sleep or poor sleep cause Alzheimer's disease, they do suggest that the failure of the brain to keep its house clean by clearing away waste like amyloid-beta may contribute to the development of conditions like Alzheimer's.
And currently, we're doing a
clinical
trial in collaboration with the German Cancer Research Center with 200 women for breast cancer.
We have drug discovery processes, screening molecules, we have
clinical
trials, and then, when we think we have a drug, then we have the FDA regulatory process.
And these seem like faraway scenarios, but if you consider the fact that we might not have antibiotics for many people who have infections, we might consider the fact that we might want to allocate who actually gets to use some of these antibiotics over others, and some of these might have to be on the basis of
clinical
need, but also on the basis of pricing.
They had a
clinical
trial for a drug that they've been developing.
In the radiology case, they were new
clinical
indicators that humans can understand.
And I mentioned that to my fellowship mentor, and he, for his part, had heard the same from a colleague, about the large number of pregnant women and young adults being hospitalized in intensive care, with hard-to-manage
clinical
profiles.
Now, ruminating about upsetting events in this way can easily become a habit, and it's a very costly one, because by spending so much time focused on upsetting and negative thoughts, you are actually putting yourself at significant risk for developing
clinical
depression, alcoholism, eating disorders, and even cardiovascular disease.
That day changed my
clinical
practice and ultimately my career.
I figured the minute that everybody else heard about this, it would be routine screening, multi-disciplinary treatment teams, and it would be a race to the most effective
clinical
treatment protocols.
What I had thought of as simply best
clinical
practice I now understand to be a movement.
And what's more, we're starting to do
clinical
trials with more children to figure out whether this has a protective effect generally.
TR: So right now, you're doing
clinical
trials in clinics.
We see how a handful of patients responds to treatment in a
clinical
trial, and we bring drugs to a national market.
There was a second, more accurate story of autism which had been lost and forgotten in obscure corners of the
clinical
literature.
Coincidentally, at the same time, the first easy-to-use
clinical
tests for diagnosing autism were introduced.
We're running a small
clinical
study at Stanford, where we treat Alzheimer's patients with mild disease with a pint of plasma from young volunteers, 20-year-olds, and do this once a week for four weeks, and then we look at their brains with imaging.
Why is that those vaccines are just going into
clinical
trials now?
As for Ebola, there is absolutely no market at all, so the only reason we have two vaccines in late-stage
clinical
trials now, is actually because of a somewhat misguided fear.
Do you know that it takes years for a drug to go from an idea to being tested on cells in a laboratory, to animal studies, to then
clinical
trials on humans, finally to go through a regulatory approval process, to be available for your doctor to prescribe to you?
Well, it turns out that those cells used in that laboratory, they're male cells, and the animals used in the animal studies were male animals, and the
clinical
trials have been performed almost exclusively on men.
And these technologies were very promising, but the problem was that they were either inefficient, or they were difficult enough to use that most scientists had not adopted them for use in their own laboratories, or certainly for many
clinical
applications.
I think that we will see
clinical
application of this technology, certainly in adults, within the next 10 years.
I think that it's likely that we will see
clinical
trials and possibly even approved therapies within that time, which is a very exciting thing to think about.
This raises a number of ethical questions that we have to carefully consider, and this is why I and my colleagues have called for a global pause in any
clinical
application of the CRISPR technology in human embryos, to give us time to really consider all of the various implications of doing so.
This is an investigational technology, but, in
clinical
trials, we're seeing a 44 to 64 percent decrease in chronic pain patients.
And when it comes to human studies, the scientific gold standard is the randomized
clinical
trial, or RCT.
Randomized
clinical
trials are incredible tools, and, in fact, the US Food and Drug Administration often requires at least two to be conducted before a new drug can be marketed.
So, the next time you see a headline about a new miracle cure or the terrible danger posed by an everyday substance, try to learn more about the original study and the limitations inherent in any epidemiological study or
clinical
trial before jumping to conclusions.
Even though we now know much more about the systems that govern the human body, these Greek ideas about sadness resonate with current views, not on the sadness we all occasionally feel, but on
clinical
depression.
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