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Angiogenesis in sentence

29 examples of Angiogenesis in a sentence

And as well, cancer tumors require a process called angiogenesis, which is really, the tumor recruits the blood vessels to itself to supply itself with nutrients so it can grow.
Without angiogenesis, the tumor remains the size of a pinpoint and it's not harmful.
So angiogenesis is really a central process to the pathogenesis of cancer.
The revolution is called angiogenesis, and it's based on the process that our bodies use to grow blood vessels.
It does this through an elaborate and elegant system of checks and balances, stimulators and inhibitors of angiogenesis, such that, when we need a brief burst of blood vessels, the body can do this by releasing stimulators, proteins called angiogenic factors, that act as natural fertilizer, and stimulate new blood vessels to sprout.
When those excess vessels are no longer needed, the body prunes them back to baseline, using naturally-occurring inhibitors of angiogenesis.
And in these situations, angiogenesis is out of balance.
And when angiogenesis is out of balance, a myriad of diseases result.
In total, there are more than 70 major diseases affecting more than a billion people worldwide, that all look on the surface to be different from one another, but all actually share abnormal angiogenesis as their common denominator.
And this realization is allowing us to re-conceptualize the way that we actually approach these diseases, by controlling angiogenesis.
Dr. Judah Folkman, who was my mentor and who was the pioneer of the angiogenesis field, once called this "cancer without disease."
So the body's ability to balance angiogenesis, when it's working properly, prevents blood vessels from feeding cancers.
In fact, if you actually block angiogenesis and prevent blood vessels from ever reaching cancer cells, tumors simply can't grow up.
And unfortunately, this late stage of cancer is the one at which it's most likely to be diagnosed, when angiogenesis is already turned on, and cancer cells are growing like wild.
So, if angiogenesis is a tipping point between a harmless cancer and a harmful one, then one major part of the angiogenesis revolution is a new approach to treating cancer by cutting off the blood supply.
So I went back to the biology of angiogenesis, and started thinking: Could the answer to cancer be preventing angiogenesis, beating cancer at its own game, so the cancers could never become dangerous?
So to look for a way to prevent angiogenesis in cancer, I went back to look at cancer's causes.
And our search for this has taken us to the market, the farm and to the spice cabinet, because what we've discovered is that Mother Nature has laced a large number of foods and beverages and herbs with naturally-occurring inhibitors of angiogenesis.
This inhibits abnormal angiogenesis, by 60 percent.
It potently inhibits angiogenesis.
Now in the lab, we can simulate tumor angiogenesis, represented here in a black bar.
Now, I've shown you a bunch of lab data, and so the real question is: What is the evidence in people that eating certain foods can reduce angiogenesis in cancer?
If you take the obese mouse and give it an angiogenesis inhibitor, it loses weight.
And, in fact, you can cycle the weight up and down simply by inhibiting angiogenesis.
And this speaks to the role of angiogenesis in regulating healthy set points.
I hope I've convinced you that for diseases like cancer, obesity and other conditions, there may be a great power in attacking their common denominator: angiogenesis.
Folkman hypothesized that this process, angiogenesis, is crucial to the tumor’s survival.
Tumors need a plentiful blood supply, so they produce factors that induce the formation of blood vessels (a process called angiogenesis).
New drugs, which have been designed to inhibit tumor angiogenesis, are showing promise in clinical trials.