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Inhibitors in sentence

30 examples of Inhibitors in a sentence

It was later developed into ACE inhibitors.
So we developed drugs to more specifically focus on serotonin, the selective serotonin reuptake inhibitors, so the SSRIs, the most famous of which is Prozac.
Now, the fascinating things are that the beta-carbolines found within that liana are MAO inhibitors of the precise sort necessary to potentiate the tryptamine.
It does this through an elaborate and elegant system of checks and balances, stimulators and inhibitors of angiogenesis, such that, when we need a brief burst of blood vessels, the body can do this by releasing stimulators, proteins called angiogenic factors, that act as natural fertilizer, and stimulate new blood vessels to sprout.
When those excess vessels are no longer needed, the body prunes them back to baseline, using naturally-occurring inhibitors of angiogenesis.
And our search for this has taken us to the market, the farm and to the spice cabinet, because what we've discovered is that Mother Nature has laced a large number of foods and beverages and herbs with naturally-occurring inhibitors of angiogenesis.
In the non-tradable sector (60-70% of the economy in advanced countries), the main growth inhibitors are weak demand, as in the United States following the financial crisis, and structural and competitive impediments to productivity, as in Japan.
To be sure, at-risk men – for example, those with a family history of prostate cancer, African-Americans, or men with enlarged prostates who are treated with 5-alpha-reductase inhibitors (whose failure to lower PSA levels could reflect increased risk of developing prostate cancer) – may want to consider getting tested.
This would explain why rats infected with T. gondii have higher levels of dopamine, and why dopamine inhibitors can suppress their parasite-induced behavior.
Neither patients nor their therapists consider the available options – including benzodiazepines like Valium and selective serotonin reuptake inhibitors like Prozac or Zoloft – as adequate treatments for anxiety.
The chemical inhibitors used in this treatment target the enzyme polymerase (PARP1), which is normally involved in the repair of DNA single-strand breaks – a common form of spontaneous DNA lesions.
In our research, we exploit this requirement to specifically target the BRCA1 or BRCA2-defective cancer cells with inhibitors of PARP.
This treatment is unlikely to cause many side effects; prolonged treatments with PARP inhibitors are well tolerated in mice.
We have shown that PARP inhibitors are effective at killing BRCA2-defective breast cancer cells, and that the tumors they cause can fully regress and disappear following treatment with a PARP inhibitor.
We are now initiating clinical trials to determine how efficient these PARP inhibitors are in the treatment of metastasized breast tumors.
It is possible that highly metastasized breast tumors might have acquired additional genetic changes causing resistance to treatment with PARP inhibitors.
Therefore, we suggest that PARP inhibitors might be more useful in the prophylactic treatment of women carrying the gene responsible for this form of inherited breast cancer.
This means that early cancerous cells should be sensitive to PARP inhibitors.
However, unlike fully developed tumors, they are not likely to have acquired many genetic changes and are therefore unlikely to have gained resistance to PARP inhibitors.
Treating women carrying BRCA1 or BRCA2 mutations with PARP inhibitors to kill cancer cells before they grow into tumors is a new and hopeful concept in cancer prevention.
However, the usefulness of this treatment relies on the fact that PARP1 inhibitors are completely non-toxic to humans.
Thus, while the use of PARP inhibitors to treat established tumors may be feasible within a few years, we could have to wait at least a decade before a prophylactic treatment for inherited breast cancer is widely available.
For example, when the new class of painkillers called Cox-2 inhibitors was introduced, regulators, physicians, and patients were unaware that these drugs could cause heart attacks and strokes.
Because the risk of heart attacks is high in older people, many of whom have arthritic pain requiring treatment with painkillers, it took six years to link Cox-2 inhibitors to a two- to three-fold increase in the risk of heart attacks.
Other substances from tobacco smoke – such as monoamine oxidase inhibitors, which have antidepressant effects –reinforce tobacco dependence, but are absent from vaporized nicotine.
It has been suggested that chemical inhibitors for this factor could make it impossible for the fly to give birth, thereby reducing tsetse populations.
Although few antidepressant drugs have been licensed for pediatric use, rates of prescribing in the under-18 age group have risen by around 60% over the past decade, with over a million children and adolescents receiving what are called selective serotonin reuptake inhibitors (SSRI’s).
I had a similar experience when I was working in his lab, trying to isolate the first inhibitors of blood-vessel growth (which were large-molecular-weight substances).
For example, studies have shown that patients of European ancestry respond better to beta blockers and ACE inhibitors than those of African descent.
In 1996, the approval of the first drug of a class called protease inhibitors led to the adoption of a multi-drug, anti-HIV regimen known as highly active antiretroviral therapy, or HAART.