Variant
in sentence
133 examples of Variant in a sentence
The economic
variant
of Machiavellianism is as powerful as the claim that political untruth can be virtuous.
This is a modern-day
variant
of the classic prescription to start tightening before inflation sets in too deeply, even if employment has not fully recovered.
Furthermore, because of the inevitable failures in the fidelity of the process, replication necessarily led also to variation (in replicable form), hence to competition among
variant
lineages for available resources.
This was a return to a
variant
of the old gold standard argument.
The Lingering Shadow of Mad Cow DiseaseOptimists are proclaiming that
variant
Creutzfeldt-Jakob disease (CJD), the human form – always fatal – of bovine spongiform encephalopathy (BSE), or “Mad Cow Disease,” is on the wane.
Obviously, given the degree of suffering and public anxiety that
variant
CJD has caused, the possibility that it is receding is welcome news.
Variant
CJD was first described in 1996, following intensive surveillance activities undertaken by the UK National CJD Surveillance Unit (NCJDSU) in Edinburgh.
Later investigations have shown that the transmitting agent in
variant
CJD shares identical biological properties with BSE’s agent, supporting a causal relationship.
Subsequent epidemiological studies in the NCJDSU indicate that individuals with
variant
CJD are likely to have consumed more meat products than control patients, further supporting a link between these disorders.
This unfortunately has been accompanied by increasing number of
variant
CJD cases in Canada, France, Ireland, Italy, Japan, Netherlands, Portugal, Saudi Arabia and the USA.
In the UK, however, the epidemic of
variant
CJD seems to have peaked in 2000 and is now in decline, with 156 cases being identified so far.
However, a retrospective study of abnormal prion protein accumulation in appendix and tonsil samples from over 12,600 people in the UK has yielded three more cases, which suggests that the level of BSE infection in the UK population is much higher than the actual number of confirmed
variant
CJD cases indicates.
One clue lies in the results of studies of the transmission of BSE and
variant
CJD in mice, which in many cases does not result in death from clinical disease, but instead can produce an asymptomatic “carrier state,” in which the disease has not yet manifested itself.
These findings have been reinforced by an extensive control study to identify risk factors for
variant
CJD, which recently identified two cases of human-to-human transmission of
variant
CJD infection through transfusions of particular types of red blood cells.
These cases are particularly interesting, because the first case resulted in the clinical onset of
variant
CJD (with typical symptoms and pathology) 6.5 years after the transfusion from a donor who, although asymptomatic at the time of donation, subsequently developed and died from CJD.
The second case involved a known recipient of such cells transfused from another asymptomatic donor who subsequently died from
variant
CJD, whereas the recipient showed no evidence of neurological disease and died of unrelated causes.
Individuals infected with BSE who remain in an asymptomatic state during their lives could represent a risk to others of potential secondary transmission of
variant
CJD through blood transfusion or surgery.
Further uncertainty regarding the future of
variant
CJD arises from the observation that the average age of the patients in the UK has not increased significantly over the past 10 years.
But
variant
CJD affects patients who are much younger than sporadic CJD patients, which might be due to either age-related exposure to BSE or age-related susceptibility.
Until we know the answers to these questions, it seems premature to decide that we are witnessing the beginning of the end of
variant
CJD.
Indeed, secondary transmission by blood transfusion or surgical instruments might even result in
variant
CJD becoming endemic in the UK population.
After all, when the chimpanzee itself was new and interesting (in the 1700’s), contemporary scholars commonly judged it to be overwhelmingly similar to the human form – so much so, that it was commonly classified as a
variant
of humans.
A
variant
of the economic argument for European unity is the claim that enhanced integration makes it easier to finance debt, because interest rates are lower.
Indeed, while it protects children from the worst forms of the disease, it does not protect anyone against the most common variant, pulmonary TB.
Indeed, we can think of the shift as a Latin American
variant
of the West’s blossoming romance with anti-establishment movements.
Since then, “new variant” Creutzfeltdt-Jakob disease has claimed roughly 300 lives.
These include: hedging export earnings – for example, via the oil options market, as Mexico does; ensuring counter-cyclical fiscal policy – for example, via a
variant
of Chile’s structural budget rule; and delegating sovereign wealth funds to professional managers, as Botswana’s Pula Fund does.
Likewise, Adam Michnik, the editor-in-chief of the national daily newspaper Gazeta Wyborcza, has accused the current PiS government of carrying out a “creeping coup” according to its own
variant
of “Putinism.”
Big Ideas from Small CountriesCAMBRIDGE – Two decades ago, many people thought that the lesson of the 1980’s was that Japan’s
variant
of capitalism was the best model, and that other countries around the world should and would follow it.
A decade ago, many thought that the lesson of the 1990’s was that the United States’
variant
of capitalism was the best model, and that other countries should and would follow.
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