Scissors
in sentence
80 examples of Scissors in a sentence
He grabbed his pen, he snatched his
scissors.
However, in the presence of the tumor, now there are molecular
scissors
that can break this molecule apart right there at the cleavable site.
I actually didn't even have a regular pair of
scissors.
She took a pair of
scissors
and cut him out of every photograph, and for years, I told myself the truth of this photograph was that you are alone, you are unsupported.
Think about it as genetic
scissors
with a microscope.
The microscope is a guide RNA, which brings the
scissors
to the place we want to cut and says, "Here it is," and the enzyme CRISPR just cuts and repairs the DNA in the way we want.
But very soon after, there was a man who took the
scissors
and cut my clothes, and then they took the thorns of the rose and stuck them in my stomach.
Basically, there's a protein that acts like a
scissors
and cuts the DNA, and there's an RNA molecule that directs the
scissors
to any point on the genome you want.
And the next tool is like
scissors
that can cut the DNA right in that spot.
Could we have the
scissors
back, please?
The second are Cas, or “CRISPR-associated” proteins which chop up DNA like molecular
scissors.
Like the viral RNA in the CRISPR immune system, the guide RNA directs Cas9 to the target gene, and the protein’s molecular
scissors
snip the DNA.
They took all knives and razors and
scissors
from his room.
And the warhead in CRISPR is this purple protein that acts like molecular
scissors
to cut DNA, breaking the double helix into two pieces.
But the most amazing feature of CRISPR is that the
scissors
can be programmed to search for, bind to and cut only a specific DNA sequence.
So when a bacterium encounters a virus for the first time, it can store a small snippet of that virus's DNA for use as a program to direct the CRISPR
scissors
to cut that viral DNA sequence during a future infection.
Remarkable researchers including Emmanuelle Charpentier, George Church, Jennifer Doudna and Feng Zhang showed six years ago how CRISPR
scissors
could be programmed to cut DNA sequences of our choosing, including sequences in your genome, instead of the viral DNA sequences chosen by bacteria.
Base editors use the programmable searching mechanism of CRISPR scissors, but instead of cutting the DNA, they directly convert one base to another base without disrupting the rest of the gene.
So if you think of naturally occurring CRISPR proteins as molecular scissors, you can think of base editors as pencils, capable of directly rewriting one DNA letter into another by actually rearranging the atoms of one DNA base to instead become a different base.
We started by taking CRISPR
scissors
and disabling the ability to cut DNA while retaining its ability to search for and bind a target DNA sequence in a programmed manner.
To those disabled CRISPR scissors, shown in blue, we attached a second protein in red, which performs a chemical reaction on the DNA base C, converting it into a base that behaves like T. Third, we had to attach to the first two proteins the protein shown in purple, which protects the edited base from being removed by the cell.
We realized that we could borrow, once again, the targeting mechanism of CRISPR
scissors
to bring the new base editor to the right site in a genome.
And when we attached that protein to the disabled CRISPR scissors, shown in blue, we produced the second base editor, which converts As into Gs, and then uses the same strand-nicking strategy that we used in the first base editor to trick the cell into replacing the nonedited T with a C as it remakes that nicked strand, thereby completing the conversion of an A-T base pair to a G-C base pair.
For example, a touch panel made for a tailor would look like this, made out of textiles, so you can cut it with
scissors
and sew it in.
And there are little chemical scissors, called restriction enzymes which cut DNA whenever they see particular patterns.
I have very high-tech equipment of gloves,
scissors
and a bucket.
Panbanisha is trying to give Nyota a haircut with a pair of
scissors.
Here Panbanisha uses scissors, instead of her hands, to groom Nyota.
Nyota tries to imitate Panbanisha by using the
scissors
himself.
Realizing that Nyota might get hurt, Panbanisha, like any human mother, carefully tugs to get the
scissors
back.
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