Proteins
in sentence
328 examples of Proteins in a sentence
The
proteins
start off folded up into intricate shapes, held together by weak chemical bonds.
Adding heat disrupts those bonds, allowing the
proteins
to unfold, uncoil, unwind and wiggle freely.
The newly liberated
proteins
bump up against their neighbors and start to form new bonds with each other, more and more as the heat increases, until finally, they're so entangled that they gel into a solid mass, a boiled egg.
According to a chemical idea called the principle of microscopic reversibility, anything that happens, like egg
proteins
seizing up, can theoretically unhappen if you retrace your steps.
But adding more heat will tangle the
proteins
further, and cooling them down will only freeze them, so here's the trick: spin them around ridiculously fast.
First, scientists dissolve boiled egg whites in water with a chemical called urea, a small molecule that acts as a lubricant, coating the
proteins'
long strands and making it easier for them to glide past each other.
That difference in velocity creates sheer stresses that repeatedly stretch and contract the
proteins
until eventually they snap back into their native shapes and stay there.
This technique works with all sorts of
proteins.
Many pharmaceuticals consist of
proteins
that are extremely expensive to produce, partly because they get stuck in tangled up aggregates, just like cooked egg whites and have to be untangled and refolded before they can do their jobs.
This spinning technique has the potential to be an easier, cheaper and quicker method than other ways to refold proteins, so it may allow new drugs to be made available to more people faster.
Boiling an egg is actually an unusual cooking process because even though it changes the way
proteins
are shaped and bound together, it doesn't actually change their chemical identity.
Most types of cooking are more like the famous Maillard reaction, which makes chemical changes that turn sugars and
proteins
into delicious caramel crunchiness and are a lot harder to undo.
These genes direct the cells to make certain proteins, and in just a few hours, the right and left sides of the embryo are chemically different.
If we zoom in even more, we see that many of cells' basic building blocks, like nucleic acids, proteins, and sugars, are inherently asymmetric.
Proteins
have complex asymmetric shapes, and those
proteins
control which way cells migrate and which way embryonic cilia twirl.
Graphs like this are often used to map communication networks, but they can represent almost any kind of network, from transport connections within a city and social relationships among people, to chemical interactions between
proteins
or the spread of an epidemic through different locations.
As they age, they stop being able to do quality control on proteins, causing the accumulation of damaged and potentially toxic nutrients, leading to excessive metabolic activity that could be fatal for them.
In the remaining brain matter, you would find
proteins
and amino acids, traces of micronutrients, and glucose.
Meanwhile,
proteins
and amino acids, the building block nutrients of growth and development, manipulate how we feel and behave.
They bind to the
proteins
in neurons' cell membranes that let charged particles in and out, and lock out positively charged particles.
Usually, tau
proteins
support tiny tubes inside our axons called microtubules.
It's thought that repeated subconcussive hits damage the microtubules, causing the tau
proteins
to dislodge and clump together.
Once the tau
proteins
start clumping together, they cause more clumps to form and continue to spread throughout the brain, even after head impacts have stopped.
Meanwhile, B-cells and helper T-cells use the information gathered from the unique antigens to start producing special
proteins
called antibodies.
We found over 200 proteins, many of which are not on the radar for malaria vaccines.
In the past 30 years, these studies have tested a small number of
proteins
in relatively few samples and usually in single locations.
We used omics intelligence to prioritize our parasite proteins, synthesize them in the lab and in short, recreated the malaria parasite on a chip.
It might take high concentrations of antibodies against multiple parasite
proteins.
So instead of programming computers, we're using things to program viruses or retroviruses or
proteins
or DNA or RNA or plants or animals, or a whole series of creatures.
That means that instead of doing this at random and seeing what happens over generations, we're inserting specific genes, we're inserting specific proteins, and we're changing lifecode for very deliberate purposes.
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