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Mutations in sentence

149 examples of Mutations in a sentence

But, enough mutations can bypass the fail-safes, driving the cell to divide recklessly.
Instead, random genetic mutations cause some giraffes to be born with longer necks, and that gives them a better chance to survive than the ones who weren't so lucky, which brings us to "survival of the fittest".
All that happens is that random genetic mutations cause the organisms carrying them to behave or develop in different ways.
That means that you can't give your gene to your doctor and ask him or her to look at it, say, to see if it has any mutations, without permission of the patent holder.
Women with certain mutations along these genes are considered to be at a significantly increased risk of developing breast and ovarian cancer.
And perhaps worst of all, for a period of several years, Myriad refused to update its test to include additional mutations that had been identified by a team of researchers in France.
Well, instead of organisms, we can start with an initial population of musical phrases, and a basic algorithm that mimics reproduction and random mutations by switching some parts, combining others, and replacing random notes.
When we hear the word radiation, it's tempting to picture huge explosions and frightening mutations, but that's not the full story.
With sufficient gene blockers, we can address many different kinds of mutations, allowing the chance to sweep out tumors, without leaving behind any bad guys.
We can add many different layers of siRNA to address different mutations and tumor defense mechanisms.
It is a very aggressive cancer, in part because it's discovered at very late stages, when it's highly advanced and there are a number of genetic mutations.
Every day, the human body evolves by accidental mutations that equally accidentally allow certain humans to persevere in dismal situations.
These aren't random mutations.
But this process has taken billions of years, and went through all sorts of iterations and mutations.
If that damage is severe enough, the cells mutations can lead to melanoma, a deadly cancer that forms in the skin's melanocytes.
Adamantium claws, weird weather-controlling habits, mutations.
In cancers, changes in the DNA called mutations are what drive these cancers to go out of control.
Around 10 years ago, I was part of the team at Johns Hopkins that first mapped the mutations of cancers.
However, scientists were able to map the mutations of this cancer and give a specific treatment that targets one of the mutations.
Random genetic mutations in orchids may result in a trait– like a scent or a shape– that, by chance, matches the needs of a single insect species.
Cell loss, mutations in chromosomes, mutations in the mitochondria and so on.
The most common kind of change in DNA is the simple swap of one letter, or base, such as C, with a different letter, such as T, G or A. In any day, the cells in your body will collectively accumulate billions of these single-letter swaps, which are also called "point mutations."
Now, most of these point mutations are harmless.
Grievous genetic diseases caused by point mutations are especially frustrating, because we often know the exact single-letter change that causes the disease and, in theory, could cure the disease.
Millions suffer from sickle cell anemia because they have a single A to T point mutations in both copies of their hemoglobin gene.
Throughout the history of medicine, we have not had a way to efficiently correct point mutations in living systems, to change that disease-causing T back into a C. Perhaps until now.
But for most point mutations that cause genetic diseases, simply cutting the already-mutated gene won't benefit patients, because the function of the mutated gene needs to be restored, not further disrupted.
But I saw the lack of a way to fix point mutations, which cause most human genetic diseases, as a major problem standing in the way.
Being a chemist, I began working with my students to develop ways on performing chemistry directly on an individual DNA base, to truly fix, rather than disrupt, the mutations that cause genetic diseases.
Among the more than 35,000 known disease-associated point mutations, the two kinds of mutations that this first base editor can reverse collectively account for about 14 percent or 5,000 or so pathogenic point mutations.
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