Mutations in sentence

149 examples of Mutations in a sentence

These different mice are different mutations that recapitulate different kinds of blindness that affect humans.

That will encourage the spread of relatively benign mutations of the most toxic varieties.

And we can then see the result of such mutations when we compare DNA sequences among us here in the room, for example.

And these mutations accumulate approximately as a function of time.

And because these mutations happen approximately as a function of time, you can transform these differences to estimates of time, where the two humans, typically, will share a common ancestor about half a million years ago, and with the chimpanzees, it will be in the order of five million years ago.

What they found was a series of mutations in a gene called SPR, which is responsible for producing serotonin, among other things.

I myself had a tumor removed from my large intestine when I was only 14. Cancer occurs when a single cell in your body acquires a set of random mutations in important genes that cause that cell to start to produce more and more and more copies of itself.

And when you have a population of fast-dividing cancer cells, if one of them acquires new mutations, which allow them to grow more quickly, acquire nutrients more successfully, invade the body, they'll be selected for by evolution.

And being a geneticist, I'm always interested to look at DNA and mutations.

It spreads through the population, has mutations that allow it to evade the immune system, and it's the only cancer that we know of that's threatening an entire species with extinction.

You might know that, so far, in just the dawn of this revolution, we know that there are perhaps 40,000 unique mutations affecting more than 10,000 genes, and that there are 500 of these genes that are bona-fide drivers, causes of cancer.

And we were very lucky to find that mutations that damage one single gene called daf-2 doubled the lifespan of the little worm.

Introduce some mutations perhaps.

The most important health challenges today are not caused by simple mutations in our genome, but rather result from a complex and dynamic interplay between genetic variation, diet, microbes and parasites and our immune response.

But as you're thinking about this, one of the interesting things is how small these mutations are and where they take place.

In a biohacker space, you can analyze your genome for mutations.

So through natural selection, over time, mutations, variations that disrupt the function of a protein will not be tolerated over time.

So blindness is a big problem, and a lot of these blind disorders come from inherited diseases, so we want to try and better understand which mutations in the gene cause the disease.

We pump energy into this and see what happens in a couple of mutations.

And what they found was that the genetic mutations that the drug targeted were far more common in women.

And the reason is because in certain individuals, they can actually have genetic changes or mutations that are not passed down from the mother or from the father, but actually start brand new in them, mutations that are present in the egg or the sperm at the time of conception but have not been passed down generation through generation within the family.

And astute clinicians tracked that down, and what they found was they were carrying mutations.

Notice, they were carrying mutations from birth that were protective, that were protecting them from going on to get AIDS.

And again, what she found was some of those individuals had mutations that were protective from birth that kept them, even though they had high lipid levels, and you can see this is an interesting way of thinking about how you could develop preventive therapies.

Many of the chemicals inside cigarettes can trigger dangerous mutations in the body’s DNA that make cancers form.

Breeders have also used other types of genetic techniques, such as random mutagenesis, which induces uncharacterized mutations into the plants.

This induces thousands of uncharacterized mutations, and this is even a higher risk of unintended consequence than many of the modern methods.

One question we asked is whether quantum tunneling plays a role in mutations in DNA.

It's speculative, but it's one of those questions that is so important that if quantum mechanics plays a role in mutations, surely this must have big implications, to understand certain types of mutations, possibly even those that lead to turning a cell cancerous.

So once a double-stranded break is made in DNA, we can induce repair, and thereby potentially achieve astounding things, like being able to correct mutations that cause sickle cell anemia or cause Huntington's Disease.

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