Molecules
in sentence
450 examples of Molecules in a sentence
When a cell lands in a droplet, it's greeted by a tiny bead, and that bead delivers millions of DNA bar code
molecules.
We incorporate the DNA bar codes into each cell's RNA
molecules.
And then we sequence billions of these combined
molecules
and use the sequences to tell us which cell and which gene every molecule came from.
But how can we discover molecular factors if we can't hold the
molecules?
An answer comes from the fact that the most informative molecules, proteins, are encoded in our DNA, which has the recipes our cells follow to make all of our proteins.
It had been known for several years that the human genome's largest influence on risk of schizophrenia comes from a part of the genome that encodes many of the
molecules
in our immune system.
They've even developed
molecules
that interfere with complement proteins, and they're starting to test them in the brain as well as the immune system.
They communicate with each other through two signaling
molecules
called Interleukin-6 and Interleukin-8.
We do it by detecting a set of very small
molecules
that circulate freely in our blood called microRNAs.
As you might know, proteins are large biological
molecules
that perform different functions within our body, like catalyzing metabolic reactions or responding to stimuli or replicating DNA, but before a protein is expressed or produced, relevant parts of its genetic code present in the DNA are copied into the messenger RNA, so this messenger RNA has instructions on how to build a specific protein, and potentially it can build hundreds of proteins, but the one that tells them when to build them and how many to build are microRNAs.
So microRNAs are small
molecules
that regulate gene expression.
So imagine trying to differentiate two molecules, extremely similar, extremely small.
We have drug discovery processes, screening molecules, we have clinical trials, and then, when we think we have a drug, then we have the FDA regulatory process.
You've got a long snout that has 200 million scent receptors in it, and you have wet nostrils that attract and trap scent molecules, and your nostrils even have slits so you can take big nosefuls of air.
And you can have what we call organic molecules, and these are the bricks of life, and you can have fossils, and you can minerals, biominerals, which is due to the reaction between bacteria and rocks, and of course you can have gases in the atmosphere.
Now, what you can't see is that our genetic program instructs these bacteria to each produce small molecules, and these
molecules
travel between the thousands of individual bacteria telling them when to turn on and off.
Now, since these bacteria specifically localize to tumors, we've been programming them to not only detect cancer but also to treat cancer by producing therapeutic
molecules
from within the tumor environment that shrink the existing tumors, and we've been doing this using quorum sensing programs like you saw in the previous movies.
But which
molecules
should we search for?
And that theory was that life produces all small molecules, so many
molecules.
Can chemistry permit making these really large
molecules
where we've never been before?
But in fact, those
molecules
are spinning at the rate of about a million revolutions per second; they're agitating back and forth their size every two nanoseconds; they're completely crowded together, they're jammed, they're bashing up against each other.
I can't define where I begin and where I end, because the atoms and the
molecules
of my arm blended with the atoms and
molecules
of the wall.
Others have sought a more scientific explanation, but I think it's fair to say that they still consider the
molecules
of life to be special.
Whatever perspective you take, it would seem pretty impossible for chemists to come in and build new parts that function within and alongside the natural
molecules
of life without somehow really screwing everything up.
Just how special are the
molecules
of life?
Now for the first time, our work suggests that maybe the
molecules
of life aren't that special.
Compare that with the small
molecules
that synthetic chemists make as drugs.
Could we make proteins with little fingers attached that specifically grab on to other
molecules?
Many small
molecules
failed during development as drugs because they just weren't specific enough to find their target in the complex environment of the human body.
So could we take those
molecules
and make them parts of new amino acids that, when incorporated into a protein, are guided by that protein to their target?
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