Mammoth in sentence

77 examples of Mammoth in a sentence

And after being totally and completely obsessed with the mammoth richness and history of Chinese culture, it was like this total relief to hear something so truly American and so truly awesome.

Simply because of this gigantic, mammoth machine called desalination.

You can do the same thing, as the costs come down, for the Carolina parakeet, for the great auk, for the heath hen, for the ivory-billed woodpecker, for the Eskimo curlew, for the Caribbean monk seal, for the woolly mammoth.

So the first large mammoth that appears on the scene is meridionalis, which was standing four meters tall weighing about 10 tons, and was a woodland-adapted species and spread from Western Europe clear across Central Asia, across the Bering land bridge and into parts of North America.

And the open grassland savannas of North America opened up, leading to the Columbian mammoth, a large, hairless species in North America.

So if we were to go deep now within the bones and the teeth that actually survived the fossilization process, the DNA which was once intact, tightly wrapped around histone proteins, is now under attack by the bacteria that lived symbiotically with the mammoth for years during its lifetime.

And using state-of-the-art clean room technology, we've devised ways that we can actually pull these DNAs away from all the rest of the gunk in there, and it's not surprising to any of you sitting in the room that if I take a mammoth bone or a tooth and I extract its DNA that I'll get mammoth DNA, but I'll also get all the bacteria that once lived with the mammoth, and, more complicated, I'll get all the DNA that survived in that environment with it, so the bacteria, the fungi, and so on and so forth.

Not surprising then again that a mammoth preserved in the permafrost will have something on the order of 50 percent of its DNA being mammoth, whereas something like the Columbian mammoth, living in a temperature and buried in a temperate environment over its laying-in will only have 3 to 10 percent endogenous.

But we've come up with very clever ways that we can actually discriminate, capture and discriminate, the mammoth from the non-mammoth DNA, and with the advances in high-throughput sequencing, we can actually pull out and bioinformatically re-jig all these small mammoth fragments and place them onto a backbone of an Asian or African elephant chromosome.

And so by doing that, we can actually get all the little points that discriminate between a mammoth and an Asian elephant, and what do we know, then, about a mammoth?

Well, the mammoth genome is almost at full completion, and we know that it's actually really big.

So a hominid genome is about three billion base pairs, but an elephant and mammoth genome is about two billion base pairs larger, and most of that is composed of small, repetitive DNAs that make it very difficult to actually re-jig the entire structure of the genome.

So having this information allows us to answer one of the interesting relationship questions between mammoths and their living relatives, the African and the Asian elephant, all of which shared an ancestor seven million years ago, but the genome of the mammoth shows it to share a most recent common ancestor with Asian elephants about six million years ago, so slightly closer to the Asian elephant.

With advances in ancient DNA technology, we can actually now start to begin to sequence the genomes of those other extinct mammoth forms that I mentioned, and I just wanted to talk about two of them, the woolly and the Columbian mammoth, both of which were living very close to each other during glacial peaks, so when the glaciers were massive in North America, the woollies were pushed into these subglacial ecotones, and came into contact with the relatives living to the south, and there they shared refugia, and a little bit more than the refugia, it turns out.

So that means that we can actually take Asian elephant chromosomes, modify them into all those positions we've actually now been able to discriminate with the mammoth genome, we can put that into an enucleated cell, differentiate that into a stem cell, subsequently differentiate that maybe into a sperm, artificially inseminate an Asian elephant egg, and over a long and arduous procedure, actually bring back something that looks like this.

Now, this wouldn't be an exact replica, because the short DNA fragments that I told you about will prevent us from building the exact structure, but it would make something that looked and felt very much like a woolly mammoth did.

Where are you going to house a mammoth?

It turns out that there are swaths of habitat in the north of Siberia and Yukon that actually could house a mammoth.

Our clan leader is telling us about how he hunted the woolly mammoth on the tundra that day.

The same thing happens when we look at the cave painting version of the story, the book about the mammoth hunt, the play, the radio broadcast, the television show or the movie.

Or maybe you're even the woolly mammoth.

Should we bring back the woolly mammoth?

A thousand years later, a mammoth died in southern Germany.

That's a National Geographic image of what is called the mammoth steppe, what the far north, the sub-Arctic and Arctic region, used to look like.

Asian elephants are the closest relative to the woolly mammoth, and they're about the same size, genetically very close.

So we're working with George Church at Harvard, who has already moved the genes for four major traits from the now well-preserved, well-studied genome of the woolly mammoth, thanks to so-called "ancient DNA analysis."

You can get a proxy, as it's being called by conservation biologists, of the woolly mammoth, that is effectively a hairy, curly-trunked, Asian elephant that is perfectly comfortable in the sub-Arctic.

When Mondo Burger, a mammoth fast-foot chain, opens across the street, it looks like Good Burger is history, until Ed formulates a secret sauce that brings hundreds of new customers to their door.

The plodding storyline of Dietrich being torn between two men, becoming a mammoth cabaret star, and fighting for the custody of her child is jumbled and often feels like bits of three separate films half-baked together.

Related words