Malaria
in sentence
933 examples of Malaria in a sentence
And so we've been working with a charity called Medical Detection Dogs to see whether we can train them to learn the smell of
malaria.
Now, three of the socks had been worn by children who were uninfected, and just one of the socks was worn by a child who was infected with
malaria.
And let's see if you can see when she senses the
malaria.
Now what we're going to do is Sarah's going to change the pots around a little bit; she's going to take the one with
malaria
away.
And we're just going to have four pots that are containing socks from children that had no
malaria.
But it is really incredible, and when we do this, what we find is that these dogs can correctly tell us when somebody's infected with
malaria
81% of the time.
So we really are looking at deploying dogs in countries, and particularly at ports of entry, to detect people who have
malaria.
Imagine a patch that you wear on the skin that would detect in your sweat when you're infected with
malaria
and change colour.
Or something a little bit more technical perhaps, a smartwatch that would alert you when you're infected with
malaria.
This could completely revolutionise the way that we track the spread of diseases, the way that we target our control efforts and respond to disease outbreaks, ultimately helping to lead to the eradication of malaria, and even beyond
malaria
for other diseases that we already know have a smell.
Today, tuberculosis, or TB, is still one of the world’s biggest infectious killers, causing more deaths than
malaria
or even HIV and AIDS.
Why? Well there's only a few diseases that account for the vast majority of those deaths: diarrhea, pneumonia and
malaria.
For example, there's more money put into baldness drugs than are put into
malaria.
Now,
malaria
is of course transmitted by mosquitos.
And that's where we saw the
malaria
map shrinking.
And so as these elements come together, I'm quite optimistic that we will be able to eradicate
malaria.
They looked at malaria, diarrheal disease, pneumonia, iron deficiency anemia, and looked at what the consequences could be in 2050.
And unexpectedly, in one of our preclinical studies, we found that a 70-year-old
malaria
drug was able to stop the immune cells from internalizing the nanoparticles so that they could escape the liver and continue their journey to their goal, the tumor.
In fact, every two minutes, a child under the age of two dies from
malaria.
Now we face many challenges when it comes to tackling malaria, but one of the problems that we have is actually finding people who are infected with
malaria
in the first place.
If this was to happen in the
malaria
system, it might make sense that it would be something to do with odor that they manipulate, because odor is the key.
Now some of the participants were infected with malaria, and some of them were uninfected, but importantly, none of the children had any symptoms whatsoever.
Now using this method with our
malaria
samples, we were able to find out what the mosquito was detecting, and we found the malaria-associated compounds, mainly aldehydes, a group of compounds that smelled, that signified the
malaria
signal here.
So now we know what the smell of
malaria
is, and we've used the mosquito as a biosensor to tell us what the smell of
malaria
actually is.
So we wanted to know, could we actually train dogs to learn the smell of
malaria?
Now three of the socks have been worn by children who were uninfected, and just one of the socks was worn by a child who was infected with
malaria.
And let's see if you can see when she senses the malaria, and if she senses the
malaria.
Now Sarah is going to actually change the pots around a little bit, and she's going to take the one with
malaria
away, and we're just going to have four pots that are containing socks from children that had no malaria, so in theory, Freya should go down the line and not stop at all.
But it is really incredible, and when we do this, what we find is that these dogs can correctly tell us when somebody is infected with
malaria
81 percent of the time.
Imagine a patch that you wear on the skin that would detect in your sweat when you're infected with
malaria
and change color.
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