Light
in sentence
5770 examples of Light in a sentence
Or in regular, but in three dimensions, where the thing that changes is the light, not the pixels' position.
When you turn on the light, actually you see this.
It doesn't need
light.
But on this side, it has sugary Gummy Bears, to diffuse the
light
more slightly.
You can imagine that then maybe you can use a pure protein to guide light, and so we've made optical fibers.
Well, there are many molecules that exist in nature which are able to convert
light
into electricity.
If we install these molecules in neurons somehow, then these neurons would become electrically drivable with light, and their neighbors, which don't have this molecule, would not.
There's one other magic trick you need to make this happen: the ability to get
light
into the brain.
There's a certain alga that swims in the wild, and it needs to navigate towards
light
in order to photosynthesize optimally.
And it senses
light
with a little eyespot, which works not unlike how our eye works.
In its membrane, or its boundary, it contains little proteins that indeed can convert
light
into electricity.
When blue
light
hits it, it opens a little hole and allows charged particles to enter the eyespot; that allows this eyespot to have an electrical signal, just like a solar cell charging a battery.
And the next thing you know, you have a neuron which can be activated with
light.
And then when you shine
light
on the entire network, just that cell type will be activated.
And when the
light
turns off, these cells go back to normal; there don't seem to be adverse events.
To do that, we came up with a very simple paradigm in collaboration with the Fiorillo group, where, if the animal goes to one side of this little box, it gets a pulse of
light.
And we'll make different cells in the brain sensitive to
light.
The animal goes to the right-hand side and pokes his nose there and gets a flash of blue
light
every time he does it.
A flash of
light
occurs.
And the same tone is going to play, and the
light
is going to flash again.
We found molecules called halorhodopsins or archaerhodopsins, that respond to green and yellow
light.
And they do the opposite of the molecule I told you about before, with the blue
light
activator, channelrhodopsin.
This animation tries to explain this concept where we made these cells sensitive to being turned off with light, and we beam
light
in, and just for the time it takes to shut down a seizure, we're hoping to be able to turn it off.
So far, we haven't seen overt reactions of any severity to these molecules or to the illumination of the brain with
light.
On the other hand,
light
can still get into the eye.
Light
is converted to electricity on them.
But the implications of being able to control seizures or epilepsy with
light
instead of drugs and being able to target those specifically is a first step.
With blue light, we can drive information, and it's in the form of a one.
So the challenge was, how are we going to bring
light
and expose these things?
And by night, artificial
light
in each one emanates and comes out to the outside.
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