Lifespan
in sentence
105 examples of Lifespan in a sentence
While CFLs are more expensive to buy, they are much cheaper over their lifespan, because they use much less energy (even more so with the cost of CO2 factored into taxes on electricity).
At the same time, all countries must acknowledge that extending the
lifespan
of the Kyoto Protocol will not solve the problem of climate change, and that a new or additional legal framework that covers all countries is needed.
Yet men all over the world tune in to American-made fantasies of male bonding and male escape – escape from the bonds of work and domesticity, and, if only for a youthful period of the male lifespan, from long-term commitment to women themselves.
The drug Riluzole, which blocks the release of glutamate, is the only available treatment for MND, and it extends a patient’s
lifespan
by only about three months.
Though those patients showed no improvement, such transplants appeared to extend
lifespan
and delay weakness in studies of mice with motor-neuron damage.
One microlife represents 30 minutes of an average young adult’s expected
lifespan.
It would also mean looking objectively at the concept and aims of international development cooperation beyond the
lifespan
of the United Nations’ Millennium Development Goals (MDGs).
Today, the average online
lifespan
of proxy servers in China is a mere 30 minutes, and 17,000 Internet cafes have been shut down.
Further advances in medical technology could extend this
lifespan
by 30% or more during this century.
As a result,
lifespan
inequality is lower than it has been for two centuries.
The price charged to consumers would rise gradually from $0.06/kilowatt-hour to the full cost of $0.16/kilowatt-hour, but over a phase-in period of, say, 40 years (the
lifespan
of the newest of today’s coal plants).
Since 1975, the nominal annual premium on the 30-year Treasury bill has averaged 2.2%: in other words, over its lifespan, the 30-year nominal T-bill yields are 2.2 percentage points more than the expected average of future short-term nominal T-bill rates.
When fed to highly cancer-susceptible mice, the tomatoes significantly extended the mice’s
lifespan.
While many of science’s promises have been fulfilled – notably, the dramatic extension of the human
lifespan
and of leisure time – many others have been only partly achieved, or not at all.
Unlike Japan, for example, with its de facto one-party government for most of the period since 1945, the
lifespan
of Turkish governments averaged around 14 months between 1960 and 2000.
By then, Proctor had exercised a complete monopoly over the production, distribution, and marketing of the bean for more than half of the patent’s
lifespan.
Its executives would have incentives to plan investments with a view to the decades-long
lifespan
of an asset, rather than gearing projects to political cycles measured in months or years.
Can an algorithm, however well researched and carefully crafted, ever really capture the relationship between happiness and factors like income, health, lifespan, and education?
They showed this type of agent could extend the
lifespan
of a laboratory animal by up to 50%.
If built, the world would commit a large share of the remaining carbon budget to high-carbon infrastructure with a
lifespan
of 40-50 years.
De Grey believes that even modest progress in this area over the coming decade could lead to a dramatic extension of the human
lifespan.
You might think that many genes would have to be changed to extend
lifespan
– genes affecting muscle strength, wrinkles, dementia, and so forth.
For example, single-gene changes can double the
lifespan
of the small roundworm C. elegans, the animal in which such genes were first identified, and they have extended the
lifespan
of mice, which are mammals like us, by up to 50%.
Most longevity genes are “master control genes,” which extend
lifespan
by changing the activities of many subordinate genes and processes.
For example, when the C. elegans daf-2 gene is impaired,
lifespan
is doubled, partly because a protein called FoxO is activated.
FoxO, in turn, extends
lifespan
by activating a diverse array of cell-protective genes, including genes that strengthen the immune system, improve DNA repair, accelerate the clearance of damaged proteins, counteract oxidative damage, and help proteins maintain their proper shape.
Inhibiting the mouse’s insulin or IGF-1 receptor (daf-2) genes, or other genes needed for insulin or IGF-1 action, can extend mouse lifespan, sometimes dramatically.
However, studies have shown that very weak impairment of IGF-1 action can increase animal
lifespan
with little effect on body size.)
If animal
lifespan
genes also affect our lifespan, can we make a drug that targets the proteins they encode to slow our aging and protect us from age-related disease?
In C. elegans, there are many different molecular routes to FoxO activation, and activating more than one at the same time can produce spectacular (six-fold or greater)
lifespan
increases.
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