Example collocations logo

Guide in sentence

1097 examples of Guide in a sentence

The part that's amazing about it is that the guide RNA, only 20 letters of it, are what target the system.
The guide RNA and the Cas9 protein complex together go bouncing along the genome, and when they find a spot where the guide RNA matches, then it inserts between the two strands of the double helix, it rips them apart, that triggers the Cas9 protein to cut, and all of a sudden, you've got a cell that's in total panic because now it's got a piece of DNA that's broken.
For example, we don't know why some guide RNAs work really well and some guide RNAs don't.
And once we see that, maybe we can guide brain cancer surgeons towards taking only the tumor and leaving the healthy brain alone.
He lived out the remainder of his days isolated and tight-lipped, never finding a way to express himself, and I didn't yet have the tools to guide him.
There, we have agreed-upon, fairly clear benchmarks, and we have laws of nature to guide us.
So we must ensure that we have the very best evidence to guide us.
They argue that metaphors really do shape the way we experience the world, and that they can even act as a guide for future actions, like self-fulfilling prophecies.
Who is going to guide, who is going to control, and who is going to create those norms?
And off to the side are always going to be rich examples of exactly what you're seeing, to help guide you.
I was a surfer, a social science student, a friend to good people, a loved brother and son, an outdoor recreation guide, and eventually, a youth worker.
Now, HAL was a sentient computer designed to guide the Discovery spacecraft from the Earth to Jupiter.
They have been bouncing around from century to century since 1492, when in the first grammar guide of the Spanish language, Antonio de Nebrija, set a clear and simple principle for our spelling: "... thus, we have to write words as we pronounce them, and pronounce words as we write them."
The case of C, S and Z is interesting, because it shows that the phonetic approach must be a guide, but it can't be an absolute principle.
I thought perhaps if I was hanging on long enough, that would guide me through the 18 minutes.
Well, a good guide is to think, "What did we do last time the rich world got serious about developing another region of the world?"
Finally, when your girl is, let's say, on her bike on the top of the steep hill that she insists she's too scared to go down, guide her to access her bravery.
This is about the life ahead of her and that she has the tools to handle and assess all the dangers that we cannot protect her from, all the challenges that we won't be there to guide her through, everything that our girls here and around the world face in their future.
And then I met Yoyo, who is the native Rapa Nui-an guide, and if you look at Yoyo's face, you kind of figure out where they got it.
But don't give up on the numbers altogether, because if you do, we'll be making public policy decisions in the dark, using nothing but private interests to guide us.
Just as a forensic sketch artist uses limited descriptions to piece together a picture using their knowledge of face structure, the imaging algorithms I develop use our limited telescope data to guide us to a picture that also looks like stuff in our universe.
Or to put it another way, I would love to offer you my experience-backed, evidence-tested guide to talking to your cousin about politics at your next family dinner; reorganizing the way in which your team debates new proposals; thinking about how we change our public conversation.
With only confusing signals as a guide, people with bipolar disorder develop abnormal thoughts and behaviors.
Could I create a system that was beneficial to the earth and that used nature as a guide rather than something to be feared?
But I want to share with you guys today my perspective as a geologist in how understanding earth's past can help inform and guide decisions that we make today about how to sustainably live on earth's surface.
But above all, it's the guide by which each of us builds our identity, our personality.
But doing this work, we also realized that the world, not just world leaders, but businesses and citizens like every single person in this room, lacked an actionable guide on how we can avoid a coming global food security crisis.
Like the viral RNA in the CRISPR immune system, the guide RNA directs Cas9 to the target gene, and the protein’s molecular scissors snip the DNA.
This is the key to CRISPR’s power: just by injecting Cas9 bound to a short piece of custom guide RNA scientists can edit practically any gene in the genome.
This template DNA is used as a blueprint to guide the rebuilding process, repairing a defective gene or even inserting a completely new one.
BackNext