Drugs
in sentence
2204 examples of Drugs in a sentence
And of course, in those days, there were no antidepressant drugs, and it became very, very popular.
It's very difficult to develop new drugs, and the reason it's difficult to develop new
drugs
is because in the early stages of drug development, the
drugs
are very risky, and they're very expensive.
About a third of all
drugs
drop out at that point.
When you're done with all that, what you have is a very small percentage of
drugs
that start the process actually come out the other side.
So Andrew said to me, he said, "What if we stop thinking about these as
drugs?
Let's see if we can use all the tricks of the trade to figure out how to make these
drugs
work as financial assets.
So we did some math, and it turned out you could make this work, but in order to make it work, you need about 80 to 150
drugs.
Now the good news is, there's plenty of
drugs
that are waiting to be tested.
We've been told that there's a backlog of about 20 years of
drugs
that are waiting to be tested but can't be funded.
In fact, that early stage of the funding process, that Phase I and preclinical stuff, that's actually, in the industry, called the Valley of Death because it's where
drugs
go to die.
So we did this math, and we figured out, OK, well, you need about 80 to, say, 150, or something like that,
drugs.
That cash flow is used, then, to buy that big portfolio of
drugs
that you need, and those
drugs
start working their way through that approval process, and each time they go through a phase of approval, they gain value.
We talked to people who have developed
drugs.
We actually looked at the data for drugs, over 2,000
drugs
that had been approved or denied or withdrawn, and we also ran millions of simulations.
I've told you there's enough drugs, but is there enough money?
Did you know that one of the first fertility
drugs
was made from the pee of Catholic nuns, and that even the Pope got involved?
And the crucial point about this is that you then have a fantastic assay to discover drugs, because what would you ask of the drugs, and you could do this through a high-throughput automated screening system, you'd ask the drugs, give me one thing: find me a drug that will bring the red line closer to the blue line, because that drug will be a high-value candidate that you could probably take direct to human trial and almost bypass that bottleneck that I've told you about in drug discovery with the animal models, if that makes sense.
There will be
drugs
that will do that.
We need less expensive
drugs.
Whether it's the ruthless Mexican
drugs
cartel, the Zetas, who use anonymous companies to launder profits while their drugs-related violence is tearing communities apart across the Americas.
We take
drugs
to shift the chemistries of our brains and to change our moods, and what are arguments or advertising or big ideas if not an attempt to influence someone else's mind?
By liking that Facebook page, or by sharing this piece of personal information, you've now improved my ability to predict whether or not you're using
drugs
or whether or not you get along well in the workplace.
It made therapeutic
drugs
and vaccines.
Until 2014, when my colleague and I accidentally discovered the first
drugs
that might prevent depression and PTSD.
We discovered the
drugs
in mice, and we're currently studying whether they work in humans.
And just as Jenner's discovery opened the door for all of the vaccines that followed after, the
drugs
we've discovered open the possibility of a whole new field: preventative psychopharmacology.
Beyond just drugs, we're going to use educational strategies.
Clearly, athletes have gotten more savvy about performance-enhancing
drugs
as well, and that's made a difference in some sports at some times, but technology has made a difference in all sports, from faster skis to lighter shoes.
Typically, this is accomplished in just three ways: sleep,
drugs
or alcohol, or death.
At the same time, if you ask, "Has that impacted the efficiency, how we've been able to develop drugs?" the answer is not really.
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