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Strand in sentence

85 examples of Strand in a sentence

So DNA's entering the production line from the left-hand side, and it hits this collection, these miniature biochemical machines, that are pulling apart the DNA strand and making an exact copy.
One strand can be copied directly, and you can see these things spooling off to the bottom there.
But things aren't so simple for the other strand because it must be copied backwards.
But in each one of your cells, each strand of DNA is about 30 to 40 million nanometers long.
All this field of view is a single strand of DNA.
The other strand is bundled up into the other sausage.
A single strand dipped in water that completely self-folds on its own into the letters M I T. I'm biased.
This is another part, single strand, dipped in a bigger tank that self-folds into a cube, a three-dimensional structure, on its own.
I decided to use a type of DNA origami, where you take a long strand of DNA and fold it into whatever shape or pattern you might want.
These short DNA sequences are what are going to fold the long strand into this shape that we want to make.
I mix them together, add a little bit of salt water, and then add this long strand I was telling you about, that I've stolen from a virus.
You cool it down to room temperature, and as you do, those short strands do the following thing: each one of them binds that long strand in one place, and then has a second half that binds that long strand in a distant place, and brings those two parts of the long strand close together so they stick together.
So the net effect of all 250 of these strands is to fold the long strand into the shape you're looking for.
In this hospital in South Africa, patients that came in with, say, a broken leg, to wait in this unventilated hallway, walked out with a multidrug-resistant strand of tuberculosis.
Just for comparison's sake, the diameter of an average strand of hair is about 100 microns.
So we're looking at something much, much smaller than a single strand of hair.
Let's take a look at the interconnected web we saw a few moments ago, and let's focus on just one strand between the US and Mexico.
Now, remember, this is only looking at one strand of the production chain between the US and Mexico, so multiply this out across all of the strands.
When we synthesize it, it comes single-stranded, so we can take the blue strand in one tube and make an orange strand in the other tube, and they're floppy when they're single-stranded.
But to do it, you need a long, single strand of DNA, which is technically very difficult to get.
Double strand again, but inside them, they're infected with a virus that has a nice, long, single-stranded genome that we can fold like a piece of paper.
Each one has a left half that binds the long strand in one place, and a right half that binds it in a different place, and brings the long strand together like this.
The net action of many of these on that long strand is to fold it into something like a rectangle.
Now, we can't actually take a movie of this process, but Shawn Douglas at Harvard has made a nice visualization for us that begins with a long strand and has some short strands in it.
That holds the long strand like this.
So if you want to build a human from DNA origami, the problem is, you need a long strand that's 10 trillion trillion bases long.
And because C only pairs with G, and T only pairs with A, simply changing a C to a T on one DNA strand creates a mismatch, a disagreement between the two DNA strands that the cell has to resolve by deciding which strand to replace.
We realized that we could further engineer this three-part protein to flag the nonedited strand as the one to be replaced by nicking that strand.
This little nick tricks the cell into replacing the nonedited G with an A as it remakes the nicked strand, thereby completing the conversion of what used to be a C-G base pair into a stable T-A base pair.
And when we attached that protein to the disabled CRISPR scissors, shown in blue, we produced the second base editor, which converts As into Gs, and then uses the same strand-nicking strategy that we used in the first base editor to trick the cell into replacing the nonedited T with a C as it remakes that nicked strand, thereby completing the conversion of an A-T base pair to a G-C base pair.
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