Example collocations logo

Refractory in sentence

12 examples of Refractory in a sentence

So as a first-ever approval of a cell and gene therapy, CAR T-cell therapy has also been tested now in adults with refractory lymphoma.
In a way, this reveals a paradox of Latin American democracy: exclusive, minority governments that devalue and weaken the state are no longer acceptable, while the rise of personalismo – a concentration of power and coupled with refractory political tactics – are bringing about fragmentation and unruly governance.
Mr. Weller knocked at the door, and after a pretty long interval--occupied by the party without, in whistling a tune, and by the party within, in persuading a refractory flat candle to allow itself to be lighted--a pair of small boots pattered over the floor-cloth, and Master Bardell presented himself.
'Well, young townskip,' said Sam, 'how's mother?''She's pretty well,' replied Master Bardell, 'so am I.''Well, that's a mercy,' said Sam; 'tell her I want to speak to her, will you, my hinfant fernomenon?'Master Bardell, thus adjured, placed the refractory flat candle on the bottom stair, and vanished into the front parlour with his message.
At length Mr. Winkle began to dream that he was at a club, and that the members being very refractory, the chairman was obliged to hammer the table a good deal to preserve order; then he had a confused notion of an auction room where there were no bidders, and the auctioneer was buying everything in; and ultimately he began to think it just within the bounds of possibility that somebody might be knocking at the street door.
He guessed, likewise, by induction, that Porthos was taking his revenge for the defeat of Chantilly, when the procurator’s wife had proved so refractory with respect to her purse.
Were we then turning back to where the phenomena of central heat ruled in all their rigour and would reduce the most refractory rocks to the state of a molten liquid?
However, it was not long before they submitted to this new service, for the onager, being less refractory than the zebra, is frequently put in harness in the mountainous regions of Southern Africa, and it has even been acclimatized in Europe, under zones of a relative coolness.
Fangs!" he ejaculated at the top of his voice to a ragged wolfish-looking dog, a sort of lurcher, half mastiff, half greyhound, which ran limping about as if with the purpose of seconding his master in collecting the refractory grunters; but which, in fact, from misapprehension of the swine-herd's signals, ignorance of his own duty, or malice prepense, only drove them hither and thither, and increased the evil which he seemed to design to remedy.
Some of these were settled by the men-at-arms with brief ceremony; the shafts of their battle-axes, and pummels of their swords, being readily employed as arguments to convince the more refractory.
After these ceremonies were past, and after all his good things were brought into my little apartment, we began to consult what was to be done with the prisoners we had; for it was worth considering whether we might venture to take them with us or no, especially two of them, whom he knew to be incorrigible and refractory to the last degree; and the captain said he knew they were such rogues that there was no obliging them, and if he did carry them away, it must be in irons, as malefactors, to be delivered over to justice at the first English colony he could come to; and I found that the captain himself was very anxious about it.
As for him, he believed, at the most, that his ear was a little refractory.