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Paracetamol in sentence

15 examples of Paracetamol in a sentence

Alcohol can also alter the function of the enzyme that breaks down Acetaminophen, the active ingredient in pain relievers like Tylenol and paracetamol.
However, 10 years ago, a hypothesis was proposed that the use of paracetamol may increase the risk of developing asthma.
Substitution of paracetamol for aspirin, researchers proposed, may have led to an enhanced allergic immune response, thereby increasing susceptibility to asthma and other allergic disorders.
Since then, a number of epidemiological studies have reported an association between asthma and exposure to paracetamol in the womb, in childhood, and in adulthood.
These studies led to the suggestion that the use of paracetamol may represent an important risk factor in the development of asthma.
The children’s parents or guardians completed written questionnaires about current symptoms of asthma, rhinitis (hayfever), and eczema, and about several risk factors, including use of paracetamol for fever in the child’s first year of life and frequency of paracetamol use in the past 12 months.
The study identified that the reported use of paracetamol for fever in the first year of life was associated with symptoms of asthma in the six- and seven-year-old children.
A dose-dependent association between asthma symptoms at 6-7 years and paracetamol use in the previous 12 months was also observed.
Similar associations were observed between the use of paracetamol and the risk of severe asthma symptoms.
The proportion of asthma cases that could be attributed to exposure to paracetamol was calculated to be between 22% and 38%.
This suggests that the potential effect of paracetamol is not restricted to the airways and may affect a number of organ systems.
Identifying the potential mechanisms that might underlie the association between paracetamol and asthma (and other allergic disorders) was not a part of this study.
For example, it is known that viral respiratory tract infections in infancy such as respiratory syncytial virus (RSV) are associated with an increased risk of asthma in later childhood and that paracetamol use for such episodes could have caused confounding in the study.
What is agreed is the need for randomized controlled trials of the long-term effects of repeated use of paracetamol in children.
Pending the results of such research, paracetamol remains the preferred drug to relieve pain and fever in childhood, to be used in accordance with WHO guidelines, which recommend that it should be reserved for children with a high fever (38.5Co or above).