Molecular
in sentence
279 examples of Molecular in a sentence
Like the viral RNA in the CRISPR immune system, the guide RNA directs Cas9 to the target gene, and the protein’s
molecular
scissors snip the DNA.
And what I want to do is write
molecular
programs, potentially to build technology.
So my friends,
molecular
programmers, and I have a sort of biomolecule-centric approach.
My little group of
molecular
programmers are trying to refashion all of these parts from DNA.
If we succeed, what will
molecular
programming look like?
And what happens if you water and feed that seed appropriately, is it will do a developmental computation, a
molecular
computation, and it'll build an electronic computer.
And if I haven't revealed my prejudices already, I think that life has been about
molecular
computers building electrochemical computers, building electronic computers, which together with electrochemical computers will build new
molecular
computers, which will build new electronic computers, and so forth.
And for
molecular
programming, the question is how does your cell phone know when to stop growing?
But for
molecular
programming, our question is, how many molecules do we need to put in that seed to get a cell phone?
You have your
molecular
compiler, you can do whatever you want.
And the point of this, if you didn't catch that, is that tiles are a kind of
molecular
program and they can output patterns.
So, what we've done is we've figured out a way to have a
molecular
program know when to stop going.
It's a
molecular
computer building an electronic computer.
And the computations that it uses, they're
molecular
computations, and in order to understand this and get a better handle on it, as Feynman said, you know, we need to build something to understand it.
You know, so this is all very cool, but what I'd like you to take from the talk, hopefully from some of those big questions, is that this
molecular
programming isn't just about making gadgets.
I mean, big piece at the
molecular
level.
After all, that's certainly what modern
molecular
biology says about us.
We will go into the third dimension and there's been tremendous progress, just in the last few years, of getting three-dimensional, self-organizing
molecular
circuits to work.
And the other theory is that we smell
molecular
vibrations.
It’s very hard to explain this by
molecular
recognition.
Now, the slight fly in the ointment is this: that if we smell
molecular
vibrations, we must have a spectroscope in our nose.
And the warhead in CRISPR is this purple protein that acts like
molecular
scissors to cut DNA, breaking the double helix into two pieces.
The results of our efforts are
molecular
machines called "base editors."
So if you think of naturally occurring CRISPR proteins as
molecular
scissors, you can think of base editors as pencils, capable of directly rewriting one DNA letter into another by actually rearranging the atoms of one DNA base to instead become a different base.
While many of these diseases are thought to be treatable by correcting the underlying mutation in even a modest fraction of cells in an organ, delivering
molecular
machines like base editors into cells in a human being can be challenging.
Continuing to develop new
molecular
machines that can make all of the remaining ways to convert one base pair to another base pair and that minimize unwanted editing at off-target locations in cells is very important.
So one approach we’re taking is to try to design drugs that function like
molecular
Scotch tape, to hold the protein into its proper shape.
Because the results of it were so spectacular that if it worked it was going to change everybody's goddamn way of doing
molecular
biology.
The clock is a
molecular
oscillator, the details here are not important at all, I don't want you to look at the names of these things on the board, but I want to point out that the clock is essentially the same in animals such as fruit flies, which my lab uses in our studies, and in mammals like mice or humans.
On a
molecular
level, I believe that that insight is the unifying theme for every talk you have seen so far at TED and will continue as we of course embark on this journey here on this tiny planet, on the ledge, on the precipice, as we are seeing, yes, death is inevitable.
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