Genome
in sentence
369 examples of Genome in a sentence
(Applause and cheers) Whereas the human
genome
identifies all genes involved in sequencing human DNA, the growing database of media imprints will eventually allow me to determine the media DNA for a specific person.
We can now do that same
genome
project in the order of two to eight hours.
So in the last decade, a large number of genomes have been added: most human pathogens, a couple of plants, several insects and several mammals, including the human
genome.
Of those roughly 29 million genes, we only have around 24,000 in our
genome.
Our first thought about synthetic genomics came when we sequenced the second
genome
back in 1995, and that from mycoplasma genitalium.
So even if somebody made the smallpox genome, that DNA itself would not cause infections.
It reassembles its
genome
after this radiation burst in about 12 to 24 hours, after its chromosomes are literally blown apart.
Here's an actual picture of what happens: the top of this shows the
genome
after 1.7 million rads of radiation.
After these genomes are synthesized, the first step is just transplanting them into a cell without a
genome.
And this is increasingly peculiar, because about 20 years ago, when they started delving into the genome, they thought it would probably contain around 100,000 genes.
We now think there are likely to be only just over 20,000 genes in the human
genome.
That was a project which aimed to read one copy of the human
genome.
So, this little thingamajig has a
genome
that's 200 times the size of yours.
We will have a 1,000-dollar
genome
within the next five to eight years.
So we're working with George Church at Harvard, who has already moved the genes for four major traits from the now well-preserved, well-studied
genome
of the woolly mammoth, thanks to so-called "ancient DNA analysis."
We did Haemophilus influenzae and then the smallest
genome
of a self-replicating organism, that of Mycoplasma genitalium.
And as soon as we had these two sequences we thought, if this is supposed to be the smallest
genome
of a self-replicating species, could there be even a smaller
genome?
Ham and I took two years off as a side project to sequence the human genome, but as soon as that was done we got back to the task at hand.
It was the first DNA phage, DNA virus, DNA
genome
that was actually sequenced.
When we started this out, we thought the synthesis would be the biggest problem, which is why we chose the smallest
genome.
And some of you have noticed that we switched from the smallest
genome
to a much larger one.
In 2008, we reported the complete synthesis of the Mycoplasma genitalium genome, a little over 500,000 letters of genetic code, but we have not yet succeeded in booting up that chromosome.
There's parts of the
genome
where it cannot tolerate even a single error, and then there's parts of the
genome
where we can put in large blocks of DNA, as we did with the watermarks, and it can tolerate all kinds of errors.
And we added three quotations, because with the first
genome
we were criticized for not trying to say something more profound than just signing the work.
It mutates furiously, it has decoys to evade the immune system, it attacks the very cells that are trying to fight it and it quickly hides itself in your
genome.
On any given plantation, 20 percent of the trees produce 80 percent of the crop, so Mars is looking at the genome, they're sequencing the
genome
of the cocoa plant.
Your
genome
is the entire sequence of your DNA.
Your connectome contains one million times more connections than your
genome
has letters.
Also, at one point in the story a technician saves a
genome
or record of the entire genetic code of a human being on a single floppy disk!
It probably requires some northern Europe
genome
in your blood to be enjoyed, I really do not understand how anyone be amused by something like this.
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