Extracellular
in sentence
20 examples of Extracellular in a sentence
So I said,
extracellular
matrix, which is this stuff called ECM, signals and actually tells the cells what to do.
We found some gooey material that had the right
extracellular
matrix in it, we put the cells in it, and lo and behold, in about four days, they got reorganized and on the right, is what we can make in culture.
In order to do that, however, we needed to have a method of distinguishing normal from malignant, and on the left is the single normal cell, human breast, put in three-dimensional gooey gel that has
extracellular
matrix, it makes all these beautiful structures.
We should be able to be dealing with these things at this level, and these conclusions say that growth and malignant behavior is regulated at the level of tissue organization and that the tissue organization is dependent on the
extracellular
matrix and the microenvironment.
But before we do that, I'd like you to think that at any given time when you're sitting there, in your 70 trillion cells, the
extracellular
matrix signaling to your nucleus, the nucleus is signaling to your
extracellular
matrix and this is how your balance is kept and restored.
We have made a lot of discoveries, we have shown that
extracellular
matrix talks to chromatin.
We have shown that there's little pieces of DNA on the specific genes of the mammary gland that actually respond to
extracellular
matrix.
It's the
extracellular
matrix, but in leather, it's the main building block.
But it actually turns out that your cells sit in this mesh of complicated fibers, proteins and sugars known as the
extracellular
matrix.
And it actually turns out that the
extracellular
matrix is different from every single part of the body.
So the ECM in my skin is different than the ECM in my liver, and the ECM in different parts of the same organ actually vary, so it's very difficult to be able to have a product that will react to the local
extracellular
matrix, which is exactly what we're trying to do.
So just like that, the
extracellular
matrix is incredibly diverse in three dimensions.
On top of that, the
extracellular
matrix is responsible for all wound healing, so if you imagine cutting the body, you actually have to rebuild this very complex ECM in order to get it to form again, and a scar, in fact, is actually poorly formed
extracellular
matrix.
So now, behind me is an animation of the
extracellular
matrix.
So as you see, your cells sit in this complicated mesh and as you move throughout the tissue, the
extracellular
matrix changes.
So now every other piece of technology on the market can only manage a two- dimensional approximation of the
extracellular
matrix, which means that it doesn't fit in with the tissue itself.
We submitted over 300 samples of mushrooms that were boiled in hot water, and mycelium harvesting these
extracellular
metabolites.
The egg is the largest cell in the body and is protected by a thick,
extracellular
shell of sugar and protein called the zona pellucida.
But when the bacteria grow and double and they're all participating in making these molecules, the molecule, the
extracellular
amount of that molecule, increases in proportion to cell number.
And what we do is we grow
extracellular
matrix from pigs.
Related words
Matrix
Actually
Cells
Which
Tissue
Turns
There
Single
Shown
Order
Malignant
Different
Complicated
Called
Wound
Water
Trying
Trillion
Throughout
Three-dimensional