Cells
in sentence
1993 examples of Cells in a sentence
And these are some of the
cells
that might be overactive in disorders such as epilepsy.
Every one of these
cells
is an incredible electrical device.
And this process, which takes just a millisecond or so, happens thousands of times a minute in every one of your 100 billion cells, as long as you live and think and feel.
If we could activate cells, we could see what powers they can unleash, what they can initiate and sustain.
And honestly, where we've gone through over the last 11 years, through an attempt to find ways of turning circuits and
cells
and parts and pathways of the brain on and off, both to understand the science and also to confront some of the issues that face us all as humans.
If we could turn on the electricity in one cell but not its neighbors, that'd give us the tool to activate and shut down these different
cells
to figure out what they do and how they contribute to the networks in which they're embedded.
You can think of them as little proteins that are like solar
cells.
One of the tricks you have to do is figure out how to deliver these genes to the
cells
you want and not all the other neighbors.
And you can do that; you can tweak the viruses so they hit some
cells
and not others.
And there's other genetic tricks you can play in order to get light-activated
cells.
And when the light turns off, these
cells
go back to normal; there don't seem to be adverse events.
Not only can you study what these
cells
do, what their power is in computing in the brain, you can also use this to try to figure out if we could jazz up the activity of these
cells
if indeed, they're atrophied.
So if we could figure out what
cells
they are, we could maybe find new targets for which drugs can be designed or screened against or maybe places where electrodes could be put in for people who have severe disability.
And we'll make different
cells
in the brain sensitive to light.
If these
cells
can mediate reward, the animal should go there more and more.
If you can delete
cells
for a few milliseconds or seconds, you can figure out what role they play in the circuits in which they're embedded.
This animation tries to explain this concept where we made these
cells
sensitive to being turned off with light, and we beam light in, and just for the time it takes to shut down a seizure, we're hoping to be able to turn it off.
Will the
cells
tolerate it?
The signals that are detected by the photoreceptors are transformed via various computations until finally, the layer of
cells
at the bottom, the ganglion cells, relay the information to the brain, where we see that as perception.
In many forms of blindness, like retinitis pigmentosa or macular degeneration, the photoreceptor
cells
have atrophied or been destroyed.
So what if we could take these channelrhodopsins and other molecules and install them on some of these other spared
cells
and convert them into little cameras?
And because there are so many of these
cells
in the eye, potentially, they could be very high-resolution cameras.
These cells, called glial cells, were once thought to be unimportant structural elements of the spinal cord that did nothing more than hold all the important things together, like the nerves.
But it turns out the glial
cells
have a vital role in the modulation, amplification and, in the case of pain, the distortion of sensory experiences.
These glial
cells
become activated.
Their DNA starts to synthesize new proteins, which spill out and interact with adjacent nerves, and they start releasing their neurotransmitters, and those neurotransmitters spill out and activate adjacent glial cells, and so on and so forth, until what we have is a positive feedback loop.
The future holds the promise that new drugs will be developed that are not symptom-modifying drugs that simply mask the problem, as we have now, but that will be disease-modifying drugs that will actually go right to the root of the problem and attack those glial cells, or those pernicious proteins that the glial
cells
elaborate, that spill over and cause this central nervous system wind-up, or plasticity, that so is capable of distorting and amplifying the sensory experience that we call pain.
As I approached this concrete building, these tiny little windows, barbed wire, high walls, observation towers, and on the inside, these cold, hard spaces, little light or air, the guards are screaming, the doors are clanking, there's a wall of
cells
filled with so many black and brown bodies.
They found these red circular-looking objects, and they looked, for all the world, like red blood
cells.
But she also found osteocytes, which are the
cells
that laid down the bones.
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