Cells
in sentence
1993 examples of Cells in a sentence
It tells us that these
cells
from the small airways in our lungs, actually have these hairlike structures that you would expect to see in the lung.
And we've put intestinal human
cells
in a gut on a chip, and they're under constant peristaltic motion, this trickling flow through the cells, and we can mimic many of the functions that you actually would expect to see in the human intestine.
There's fluid flowing across these cells, so we can begin to interconnect multiple different chips together to form what we call a virtual human on a chip.
Now imagine if we could take
cells
from all those different populations, put them on chips, and create populations on a chip.
Now, let's imagine a little bit what the future might look like if I could take your stem
cells
and put them on a chip, or your stem
cells
and put them on a chip.
So 100 years ago, hormones had just been discovered, and people hoped that hormone treatments were going to cure aging and disease, and now instead we set our hopes on stem cells, genetic engineering, and nanotechnology.
That red layer is a tough outer layer of dead skin, but the brown layer and the magenta layer are jammed full of immune
cells.
We target thousands upon thousands of these particular
cells
just residing within a hair's width of the surface of the skin.
So what if you've targeted
cells?
Our investigators have found that there are certain genes in the lung tumor
cells
of both women and men.
Now the average human ejaculate has about 300 million sperm cells, so it's already a competitive environment.
They keep the sperm
cells
cool so you can have frequent ejaculations.
Okay? (Laughter) So the brain is terribly simple: it's made up of four cells, and two of them are shown here.
And when these four
cells
work together in health and harmony, they create an extraordinary symphony of electrical activity, and it is this electrical activity that underpins our ability to think, to emote, to remember, to learn, move, feel and so on.
But equally, each of these individual four
cells
alone or together, can go rogue or die, and when that happens, you get damage.
It's amazing and it's occurred because there are stem
cells
in the brain, even, which can enable new myelin, new insulation, to be laid down over the damaged nerves.
We can use stem cells, and specifically we can use human stem
cells.
And human stem
cells
are these extraordinary but simple
cells
that can do two things: they can self-renew or make more of themselves, but they can also become specialized to make bone, liver or, crucially, nerve cells, maybe even the motor nerve cell or the myelin cell.
And the challenge has long been, can we harness the power, the undoubted power of these stem
cells
in order to realize their promise for regenerative neurology?
Take a skin cell, make it a master pluripotent cell, so you could then make those
cells
that are relevant to their disease, both to study but potentially to treat.
So to return to the original problem, what is the opportunity of these stem cells, or this disruptive technology, for repairing the damaged brain, which we call regenerative neurology?
It's very simple: You take a patient with a disease, let's say motor neuron disease, you take a skin sample, you do the pluripotent reprogramming, as I've already told you, and you generate live motor nerve
cells.
That's straightforward, because that's what pluripotent
cells
can do.
And what you're looking at, and this is amazing, these are living, growing, motor nerve
cells
from a patient with motor neuron disease.
So apart from seeing them grow and put out processes, we can also engineer them so that they fluoresce, but crucially, we can then track their individual health and compare the diseased motor nerve
cells
to the healthy ones.
But I want to come back to how you might use stem
cells
directly to repair damage.
The first, and I think in the long run the one that will give us the biggest dividend, but it's not thought of that way just yet, is to think about those stem
cells
that are already in your brain, and I've told you that.
All of us have stem
cells
in the brain, even the diseased brain, and surely the smart way forward is to find ways that you can promote and activate those stem
cells
in your brain already to react and respond appropriately to damage to repair it.
But the other way is to effectively parachute in cells, transplant them in, to replace dying or lost cells, even in the brain.
We took patients with multiple sclerosis and asked a simple question: Would stem
cells
from the bone marrow be protective of their nerves?
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