And we support all of that with an intensive psychotherapy program to address the despondency, despair and depression that always accompanies severe, chronic pain.

Four- to five-day-a-week psychoanalytic psychotherapy for decades and continuing, and excellent psychopharmacology.

And we are socially addicted to growth, because thanks to a century of consumer propaganda, which fascinatingly was created by Edward Bernays, the nephew of Sigmund Freud, who realized that his uncle's psychotherapy could be turned into very lucrative retail therapy if we could be convinced to believe that we transform ourselves every time we buy something more.

In rural Uganda, Paul Bolton and his colleagues, using villagers, demonstrated that they could deliver interpersonal psychotherapy for depression and, using a randomized control design, showed that 90 percent of the people receiving this intervention recovered as compared to roughly 40 percent in the comparison villages.

And we decided to take on depression, and the reason we took on depression is because it's so prevalent, and as you know, there are many treatments for depression, with medication and psychotherapy, even electroconvulsive therapy, but there are millions of people, and there are still 10 or 20 percent of patients with depression that do not respond, and it is these patients that we want to help.

The asymmetry of these connections may also help us understand why psychotherapy is often such a difficult and prolonged process, for it relies on imperfect channels of communication between brain systems involved in cognition and emotion.

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