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Mimic: Sentinel is set in New York where a sufferer of the disease Stricklers which is mentioned in the first Mimic (1997) named Marvin (Karl Geary) lives with his mom Simone (Amada Plummer) & younger sister Rosy (Alexis Dziena) in an apartment block, he can rarely venture outside his sterile room as he is apparently 'environmentally sensitive' whatever that means.