There are two historians of business at the University of Maryland, Brent Goldfarb and David Kirsch, who have done some extremely interesting work, much of it still unpublished, on the history of major innovations.

That's the technical term for the phenomenon where unflattering data gets lost, gets unpublished, is left missing in action, and they say the results described here "might have provided an early warning of trouble ahead."

One of them was positive and that was published, but six of them were negative and they were left unpublished.

Now when the Cochrane systematic reviewers were trying to collect together all of the data from all of the trials that had ever been conducted on whether Tamiflu actually did this or not, they found that several of those trials were unpublished.

But the weird thing is that 20 years later, during the crazy ride of "Eat, Pray, Love," I found myself identifying all over again with that unpublished young diner waitress who I used to be, thinking about her constantly, and feeling like I was her again, which made no rational sense whatsoever because our lives could not have been more different.

Gideon Spilett ranked among the first of those reporters: a man of great merit, energetic, prompt and ready for anything, full of ideas, having traveled over the whole world, soldier and artist, enthusiastic in council, resolute in action, caring neither for trouble, fatigue, nor danger, when in pursuit of information, for himself first, and then for his journal, a perfect treasury of knowledge on all sorts of curious subjects, of the unpublished, of the unknown, and of the impossible.

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