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Misfortune in example sentence

He never wanted to let her out of his room, not while he lived, anyway; his shocking appearance should, for once, be of some use to him; he wanted to be at every door of his room at once to hiss and spit at the attackers; his sister should not be forced to stay with him, though, but stay of her own free will; she would sit beside him on the couch with her ear bent down to him while he told her how he had always intended to send her to the conservatory, how he would have told everyone about it last Christmas - had Christmas really come and gone already? - if this misfortune hadn't got in the way, and refuse to let anyone dissuade him from it.
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